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Novel Evidence hat Attributing Affectively Salient Signal to Random Noise Is Associated with Psychosis
Catalán Alcántara, Ana
; Simons, Claudia J. P.; Bustamante Madariaga, Sonia; Drukker, Marjan; Madrazo, Aranzazu; González de Artaza Lavesa, Maider; Gorostiza, Iñigo; Van Os, Jim; González Torres, Miguel Ángel (Public Library Science, 2014-07-14)
We wished to replicate evidence that an experimental paradigm of speech illusions is associated with psychotic experiences. Fifty-four patients with a first episode of psychosis (FEP) and 150 healthy subjects were examined ... -
Novel genes and sex differences in COVID-19 severity
Castaño González, Luis Antonio; ; ; (Oxford University Press, 2022-11)
Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE ... -
Novel Golden Lipid Nanoparticles with Small Interference Ribonucleic Acid for Substrate Reduction Therapy in Fabry Disease
Beraza Millor, Marina; Rodríguez Castejón, Julen ; Miranda Gómez, Jonatan ; Del Pozo Rodríguez, Ana ; ; Solinís Aspiazu, María Ángeles (MDPI, 2023-07-12)
Substrate reduction therapy (SRT) has been proposed as a new gene therapy for Fabry disease (FD) to prevent the formation of globotriaosylceramide (Gb3). Nanomedicines containing different siRNA targeted to Gb3 synthase ... -
Novel hybrid organic/inorganic poly(thiourethane) covalent adaptable networks
(Elsevier, 2022-07)Organic-inorganic hybrid materials combine the advantages of both phases: hardness and strength of inorganic phase and elasticity and toughness of the organic matrix. In the present study, we have prepared nanocomposites ... -
Novel Hydrogels of Chitosan and Poly(vinyl alcohol) Reinforced with Inorganic Particles of Bioactive Glass
; ; Meaurio Arrate, Emiliano; ; ; Sarasua Oiz, José Ramón (MDPI, 2021-02-25)
Chitosan (CS) and poly(vinyl alcohol) (PVA) hydrogels, a polymeric system that shows a broad potential in biomedical applications, were developed. Despite the advantages they present, their mechanical properties are ... -
Novel Loci for Childhood Body Mass Index and Shared Heritability with Adult Cardiometabolic Traits
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Bilbao Catalá, José Ramón; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (Public Library Science, 2020-10-12)
The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed ... -
Novel Mean-Type Inequalities via Generalized Riemann-Type Fractional Integral for Composite Convex Functions: Some Special Examples
; ; ; ; ; De la Sen Parte, Manuel; (MDPI, 2023-02-10)
This study deals with a novel class of mean-type inequalities by employing fractional calculus and convexity theory. The high correlation between symmetry and convexity increases its significance. In this paper, we first ... -
Novel Papillomaviruses in Free-Ranging Iberian Bats: No Virus-Host Co-evolution, No Strict Host Specificity, and Hints for Recombination
García Pérez, Raquel; Ibáñez, Carlos; Godínez, José M.; Aréchiga, Nidia; Garín Atorrasagasti, Ignacio; Pérez Suárez, Gonzalo; De Paz, Oscar; Juste, Javier; Echevarría, Juan E.; Bravo, Ignacio G. (Oxford University Press, 2014)
Papillomaviruses (PVs) are widespread pathogens. However, the extent of PV infections in bats remains largely unknown. This work represents the first comprehensive study of PVs in Iberian bats. We identified four novel PVs ... -
Novel phosphine sulphide gold(I) complexes: topoisomerase I inhibitors and antiproliferative agents
; ; ; ; Rubiales Alcaine, María Gloria; ; Palacios Gambra, Francisco Javier ; Alonso Pérez, Concepción Estibaliz (RSC, 2020-05-20)
This work describes the synthesis of the gold(I) complexes of phosphine sulphides. The formation of these new derivatives has been confirmed by X-ray crystallography. The coordination of gold(I) with the sulphur atom of ... -
Novel Pixelwise Co-Registered Hematoxylin-Eosin and Multiphoton Microscopy Image Dataset for Human Colon Lesion Diagnosis
Picón Ruiz, Artzai; Terradillos Fernández, Elena; Sánchez Peralta, Luisa F.; Mattana, Sara; Cicchi, Riccardo; Blover, Benjamin J.; Arbide del Río, Nagore; Velasco Arteche, Jacques; Etxezarraga Zuluaga, María Carmen; Pavone, Francesco S.; Garrote Contreras, Estíbaliz; López Saratxaga, Cristina (Elsevier, 2022-02-07)
Colorectal cancer presents one of the most elevated incidences of cancer worldwide. Colonoscopy relies on histopathology analysis of hematoxylin-eosin (H&E) images of the removed tissue. Novel techniques such as multi-photon ... -
Novel Population Pharmacokinetic Model for Linezolid in Critically Ill Patients and Evaluation of the Adequacy of the Current Dosing Recommendation
; ; ; ; ; Isla Ruiz, Arantxazu; (MDPI, 2020-01-09)
Antimicrobial treatment in critically ill patients remains challenging. The aim of this study was to develop a population pharmacokinetic model for linezolid in critically ill patients and to evaluate the adequacy of ... -
Novel Sol-Gel Route to Prepare Eu3+-Doped 80SiO2-20NaGdF4 Oxyfluoride Glass-Ceramic for Photonic Device Applications
; ; ; ; ; Balda de la Cruz, Rolindes; (MDPI, 2023-03-05)
Oxyfluoride glass-ceramics (OxGCs) with the molar composition 80SiO2-20(1.5Eu3+: NaGdF4) were prepared with sol-gel following the “pre-crystallised nanoparticles route” with promising optical results. The preparation of ... -
Novel Thermal Management Strategy for Improved Inverter Reliability in Electric Vehicles
Trancho Olabarri, Elena; Ibarra Basabe, Edorta ; ; ; ; (MDPI, 2020-11-12)
Requirements for electric vehicle (EV) propulsion systems—i.e., power density, switching frequency and cost—are becoming more stringent, while high reliability also needs to be ensured to maximize a vehicle’s life-cycle. ... -
Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity
Alonso Pérez, Concepción Estibaliz; Fuertes Sánchez, María ; ; ; Rubiales Alcaine, María Gloria ; ; ; Palacios Gambra, Francisco Javier (Elsevier, 2018-02-22)
This work describes the synthesis of 1,2,3,4-tetrahydroquinolinylphosphine oxides, phosphanes and phosphine sulfides as well as that of quinolinylphosphine oxides and phosphine sulfides, which were synthesized in good to ... -
Novel Transcript Discovery Expands the Repertoire of Pathologically-Associated, Long Non-Coding RNAs in Vascular Smooth Muscle Cells
(MDPI, 2021-02-02)Vascular smooth muscle cells (VSMCs) provide vital contractile force within blood vessel walls, yet can also propagate cardiovascular pathologies through proliferative and pro-inflammatory activities. Such phenotypes are ... -
Novel Variant in the CNNM2 Gene Associated with Dominant Hypomagnesemia
García Castaño, Alejandro; Madariaga Domínguez, Leire; Antón Gamero, Montserrat; Mejia, Natalia; Ponce, Jenny; Gómez Conde, Sara; Pérez de Nanclares, Gustavo; De la Hoz, Ana Belén; Martínez Salazar, Rosa; Saso Jiménez, Laura; Martínez de la Piscina Martín, Idoia; Urrutia, Inés; Velasco, Olaia; Aguayo Calcena, Aníbal; Castaño González, Luis Antonio ; Gaztambide Sáenz, María Sonia (Public Library Science, 2020-09-30)
The maintenance of magnesium (Mg2+) homeostasis is essential for human life. The Cystathionine-beta-synthase (CBS)-pair domain divalent metal cation transport mediators (CNNMs) have been described to be involved in maintaining ... -
NPG–TRIS Thermal Storage System. Quantification of the Limiting Processes: Sublimation and Water’s Adsorption
De La Pinta Alonso, Noelia; Santos Moreno, Sergio; Doppiu, Stefania; Igartua Aldamiz, Josu Mirena; Palomo del Barrio, Elena; López, Gabriel Alejandro (MDPI, 2021-10-05)
The NPG–TRIS binary system (NPG = (CH3)2C(CH2OH)2 = 2,2-dimetyl-1,3-propanodiol; TRIS = NH2C(CH2OH)3 = 2-Amino-2-(hydroxymethyl)-1,3-propanediol) was intensively investigated as a thermal energy storage system, due to the ... -
NRN1 Gene as a Potential Marker of Early-Onset Schizophrenia: Evidence from Genetic and Neuroimaging Approaches
; ; ; ; ; ; ; ; ; ; ; ; Cuesta, Manuel J.; ; ; ; Callado Hernando, Luis Felipe; ; ; (MDPI, 2022)
Included in the neurotrophins family, the Neuritin 1 gene (NRN1) has emerged as an attractive candidate gene for schizophrenia (SZ) since it has been associated with the risk for the disorder and general cognitive performance. ... -
Nuclear energy: Twitter data mining for social listening analysis
Zarrabeitia Bilbao, Enara; ; Río Belver, Rosa María ; Álvarez Meaza, Izaskun (Springer, 2023)
Knowing the presence, attitude and sentiment of society is important to promote policies and actions that influence the development of different energy sources and even more so in the case of an energy source such as ... -
Nucleation and Crystallization of PA6 Composites Prepared by T-RTM: Effects of Carbon and Glass Fiber Loading
Zaldua Carazo, Nerea; Maiz, Jon; De la Calle, Amaia; Garcia Arrieta, Sonia; Elizetxea, Cristina; Harismendy, Isabel; ; Müller Sánchez, Alejandro Jesús (MDPI, 2019-10-14)
Thermoplastic resin transfer molding (T-RTM) is attracting much attention due to the need for recyclable alternatives to thermoset materials. In this work, we have prepared polyamide-6 (PA6) and PA6/fiber composites by ...