Salmonella enterica 4,5,12:b:- serotipo berriaren karakterizazioa eta etxeko dortokekin erlazionatutako arriskua

Abstract

Salmonellosis, is one of the most common toxinfection caused by bacteria of the genus Salmonella in developed countries. In general, human salmonellosis is associated with contaminated food. However, contact with animals can be an important transmission route for Salmonella. Turtles have been shown to be reservoirs of different Salmonella serotypes. Considering that these reptiles are very common domestic pets, they can be a risk for public health, especially among children. In this work, a new monophasic serotype with the antigenic formula 4,5,12:b:- has been characterized. Most of the isolates analyzed have been isolated from children under 5 years of age in different regions of Spain. By means of different molecular techniques, it has been confirmed that 4,5,12:b:- isolates are genetically related to the biphasic isolates of Paratyphi B Java and that this serotype is their possible ancestor. The great homogeneity between the studied strains suggests that the origin of the turtles infected by these strains is closely related and that in Spain turtle shops have a common distribution point that contributes to the spread of this pathogen.; Salmonelosia, herrialde garatuetako toxiinfekzio ohikoenetariko bat da, Salmonella generoko bakterioek eragindakoa. Oro har, giza salmonelosia elikagai kutsatuekin lotzen da. Hala ere, animaliekin izandako kontaktua Salmonella generoaren transmisio bide garrantzitsua izan daiteke. Dortokak Salmonella serotipo desberdinen gordailuak direla frogatu da. Narrasti hauek etxeko maskota oso ohikoak direla kontuan izanda, osasun publikorako arriskutsuak izan daitezke, batez ere haurren artean. Horregatik, lan honetan 4,5,12:b:- formula antigenikoa duen serotipo monofasiko berri bat karakterizatu da. Aztertutako isolatu gehienak 5 urtetik beherako haurretan isolatu dira, Espainiako eskualde desberdinetan. Teknika molekular ezberdinen bidez, baieztatu da 4,5,12:b:- isolatuak Paratyphi B Javako iso- latu bifasikoekin genetikoki erlazionatuta daudela eta serotipo hori dela haren arbaso posiblea. Aztertutako anduien arteko homogeneotasun handiak iradokitzen du, andui horietaz infektatutako dortoken jatorria estuki lotuta dagoela, Espainian dortoken saltokiek banaketa-puntu komuna dutela, eta horrek patogeno honen sakabanaketan laguntzen duela.