Role of proinflammatory mutations in peri‑implantitis: systematic review and meta‑analysis

Lafuente Ibáñez de Mendoza, Irene; Setién Olarra, Amaia; García de la Fuente, Ana María; Aguirre Urizar, José Manuel; Marichalar Mendia, Xabier

dc.contributor.author	Lafuente Ibáñez de Mendoza, Irene
dc.contributor.author	Setién Olarra, Amaia
dc.contributor.author	García de la Fuente, Ana María
dc.contributor.author	Aguirre Urizar, José Manuel
dc.contributor.author	Marichalar Mendia, Xabier
dc.date.accessioned	2022-01-25T13:19:13Z
dc.date.available	2022-01-25T13:19:13Z
dc.date.issued	2022-01-21
dc.identifier.citation	International journal of implant dentistry 8(1) : (2022) // Article ID 2	es_ES
dc.identifier.issn	2198-4034
dc.identifier.uri	http://hdl.handle.net/10810/55147
dc.description.abstract	PURPOSE: To perform a systematic review and meta-analysis on the presence of inflammatory polymorphisms in patients with peri-implantitis (PI). PI is the main complication associated to dental implant therapy. Although its main risk factors are history of periodontitis, poor plaque control and lack of regular maintenance, genetic susceptibility could also be a determinant factor for its appearance. Single nucleotide polymorphisms (SNP) are small mutations of the DNA that alter the osseointegration of implants. Inflammatory proteins participate in both destruction of the extracellular matrix and reabsorption of the alveolar bone. METHODS: A bibliographical research was made in PubMed, Scopus and Web of Science (keywords: "single nucleotide polymorphism", "polymorphism", "periimplantitis", "SNP" and "implant failure"). RESULTS: There is a statistically significant association of peri-implant bone loss with the homozygotic model of IL-1beta (-511) (OR: 2.255; IC: 1.040-4.889). CONCLUSIONS: Associations between inflammatory polymorphisms and PI must be taken with caution due to the heterogeneous methodological design, sample size and diagnostic criteria of the studies. Thus, more well-designed studies are needed that analyze the relationship between these and more SNP and PI.	es_ES
dc.language.iso	eng	es_ES
dc.publisher	Springer	es_ES
dc.rights	info:eu-repo/semantics/openAccess	es_ES
dc.rights.uri	http://creativecommons.org/licenses/by/3.0/es/	*
dc.subject	inflammation	es_ES
dc.subject	meta-analysis peri-implantitis	es_ES
dc.subject	single nucleotide polymorphism	es_ES
dc.subject	systematic review	es_ES
dc.title	Role of proinflammatory mutations in peri‑implantitis: systematic review and meta‑analysis	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.rights.holder	The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.	es_ES
dc.rights.holder	Atribución 3.0 España	*
dc.relation.publisherversion	https://journalimplantdent.springeropen.com/articles/10.1186/s40729-022-00400-y	es_ES
dc.identifier.doi	10.1186/s40729-022-00400-y
dc.departamentoes	Enfermería II	es_ES
dc.departamentoes	Estomatología II	es_ES
dc.departamentoeu	Erizaintza II	es_ES
dc.departamentoeu	Estomatologia II	es_ES

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The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which
permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the
original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or
other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line
to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory
regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this
licence, visit http://creativecommons.org/licenses/by/4.0/.

Except where otherwise noted, this item's license is described as The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.