dc.contributor.author | Serrano Fernández, Leyre | |
dc.contributor.author | Ruiz Iturriaga, Luis Alberto | |
dc.contributor.author | Pérez Fernández, Silvia | |
dc.contributor.author | España Yandiola, Pedro Pablo | |
dc.contributor.author | Gómez, Ainhoa | |
dc.contributor.author | González, Beatriz | |
dc.contributor.author | Uranga Echeverría, Ane | |
dc.contributor.author | Castro, Sonia | |
dc.contributor.author | Iriberri, Milagros | |
dc.contributor.author | Zalacaín Jorge, Rafael | |
dc.date.accessioned | 2023-07-07T17:13:22Z | |
dc.date.available | 2023-07-07T17:13:22Z | |
dc.date.issued | 2023-09 | |
dc.identifier.citation | International Journal of Infectious Diseases 134 : 106-113 (2023) | es_ES |
dc.identifier.issn | 1878-3511 | |
dc.identifier.uri | http://hdl.handle.net/10810/61939 | |
dc.description.abstract | Objectives
To analyze the differences in short- and long-term prognosis and the predictors of survival between patients with community-acquired Legionella and Streptococcus pneumoniae pneumonia, diagnosed early by urinary antigen testing (UAT).
Methods
Prospective multicenter study conducted in immunocompetent patients hospitalized with community-acquired Legionella or pneumococcal pneumonia (L-CAP or P-CAP) between 2002-2020. All cases were diagnosed based on positive UAT.
Results
We included 1452 patients, 260 with community-acquired Legionella pneumonia (L-CAP) and 1192 with community-acquired pneumococcal pneumonia (P-CAP). The 30-day mortality was higher for L-CAP (6.2%) than for P-CAP (5%). After discharge and during the median follow-up durations of 11.4 and 8.43 years, 32.4% and 47.9% of patients with L-CAP and P-CAP died, and 82.3% and 97.4% died earlier than expected, respectively. The independent risk factors for shorter long-term survival were age >65 years, chronic obstructive pulmonary disease, cardiac arrhythmia, and congestive heart failure in L-CAP and the same first three factors plus nursing home residence, cancer, diabetes mellitus, cerebrovascular disease, altered mental status, blood urea nitrogen ≥30 mg/dl, and congestive heart failure as a cardiac complication during hospitalization in P-CAP.
Conclusion
In patients diagnosed early by UAT, the long-term survival after L-CAP or P-CAP was shorter (particularly after P-CAP) than expected, and this shorter survival was mainly associated with age and comorbidities. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.title | Short- and long-term prognosis of patients with community-acquired Legionella or pneumococcal pneumonia diagnosed by urinary antigen testing | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2023 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND
license (http://creativecommons.org/licenses/by-nc-nd/4.0/) | es_ES |
dc.rights.holder | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S1201971223006173 | es_ES |
dc.identifier.doi | 10.1016/j.ijid.2023.05.065 | |
dc.departamentoes | Inmunología, microbiología y parasitología | es_ES |
dc.departamentoes | Medicina | es_ES |
dc.departamentoeu | Immunologia, mikrobiologia eta parasitologia | es_ES |
dc.departamentoeu | Medikuntza | es_ES |