dc.contributor.author | Bermúdez, Garazi | |
dc.contributor.author | Quiñones, Ileana | |
dc.contributor.author | Carrasco, Alejandro | |
dc.contributor.author | Gil-Robles, Santiago | |
dc.contributor.author | Amoruso, Lucia | |
dc.contributor.author | Mandonnet, Emmanel | |
dc.contributor.author | Carreiras, Manuel | |
dc.contributor.author | Catalán, Gregorio | |
dc.contributor.author | Pomposo, Iñigo | |
dc.date.accessioned | 2024-03-07T11:15:50Z | |
dc.date.available | 2024-03-07T11:15:50Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Bermúdez, G., Quiñones, I., Carrasco, A. et al. A novel cognitive neurosurgery approach for supramaximal resection of non-dominant precuneal gliomas: a case report. Acta Neurochir 165, 2747–2754 (2023). https://doi.org/10.1007/s00701-023-05755-8 | es_ES |
dc.identifier.citation | Acta neurochirurgica | |
dc.identifier.issn | 0001-6268 | |
dc.identifier.uri | http://hdl.handle.net/10810/66152 | |
dc.description | Published on 19 August 2023 | es_ES |
dc.description.abstract | Despite mounting evidence pointing to the contrary, classical neurosurgery presumes many cerebral regions are non-eloquent,
and therefore, their excision is possible and safe. This is the case of the precuneus and posterior cingulate, two interacting hubs engaged during various cognitive functions, including refective self-awareness; visuospatial and sensorimotor
processing; and processing social cues. This inseparable duo ensures the cortico-subcortical connectivity that underlies
these processes. An adult presenting a right precuneal low-grade glioma invading the posterior cingulum underwent awake
craniotomy with direct electrical stimulation (DES). A supramaximal resection was achieved after locating the superior
longitudinal fasciculus II. During surgery, we found sites of positive stimulation for line bisection and mentalizing tests that
enabled the identifcation of surgical corridors and boundaries for lesion resection. When post-processing the intraoperative
recordings, we further identifed areas that positively responded to DES during the trail-making and mentalizing tests. In
addition, a clear worsening of the patient’s self-assessment ability was observed throughout the surgery. An awake cognitive
neurosurgery approach allowed supramaximal resection by reaching the cortico-subcortical functional limits. The mapping
of complex functions such as social cognition and self-awareness is key to preserving patients’ postoperative cognitive health
by maximizing the ability to resect the lesion and surrounding areas. | es_ES |
dc.description.sponsorship | Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This research was supported by the Ikerbasque Foundation; by the Basque Government through the BERC 2022–2025 program; by the Spanish State Research Agency through BCBL Severo Ochoa excellence accreditation SEV CEX2020-001010-S; by the Fundación Científica AECC (FCAECC) through the project PROYE20005CARR; by a Juan de la Cierva Fellowship to LA (IJCI 2017 31373); by Spanish Ministry of Economy and Competitiveness through the Plan Nacional PID2021-123575OB-I00 (SCANCER) to LA and by the Health Department of the Basque Government through the project 2021333011 granted to IP. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | SPRINGER | es_ES |
dc.relation | info:eu-repo/grantAgreement/GV/BERC2022-2025 | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI/CEX2020-001010-S | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI/IJCI/ 2017 31373 | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI/PID2021-123575OB-I00 | es_ES |
dc.relation | info:eu-repo/grantAgreement/GV/2021333011 | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject | Precuneus | es_ES |
dc.subject | Posterior cingulum | es_ES |
dc.subject | Cognitive awake surgery | es_ES |
dc.title | A novel cognitive neurosurgery approach for supramaximal resection of non-dominant precuneal gliomas: A case report | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. | es_ES |
dc.relation.publisherversion | https://link.springer.com/journal/701 | es_ES |
dc.identifier.doi | 10.1007/s00701-023-05755-8 | |