Enantioselective α-Aminophosphonate Functionalization of Indole Ring through an Organocatalyzed Friedel-Crafts Reaction
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Date
2018-12-17Author
Maestro Burzaco, Aitor
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The Journal of Organic Chemistry 84(2) : 1094-1102 (2018)
Abstract
Chiral phosphoric acids efficiently catalyze the asymmetric
Friedel−Crafts reaction of several indoles with α-iminophosphonates
to afford enantioenriched hybrid α-aminophosphonate
functionalized indole derivatives.