Browsing by Author "M. de Pancorbo, Marian"
Now showing items 1-20 of 40
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A Genome-Wide Study of Single-Nucleotide Polymorphisms in MicroRNAs and Further In Silico Analysis Reveals Their Putative Role in Susceptibility to Late-Onset Alzheimer's Disease.
Herrera Espejo, Soraya; Santos Zorrozúa, Borja ; Álvarez González, Paula; Martín Guerrero, Idoia; Martínez de Pancorbo Gómez, María de los Angeles ; García-Orad Carles, África ; López López, Elixabet (Springer Nature, 2020-09-06)Late-onset Alzheimer's disease (LOAD) is a neurodegenerative disorder of growing relevance in an aging society for which predictive biomarkers are needed. Many genes involved in LOAD are tightly controlled by microRNAs ... -
A novel form of human disease with a protease-sensitive prion protein and heterozygosity methionine/valine at codon 129: Case report
Rodríguez Martínez, Ana B.; Garrido Urkullu, Joseba M.; Zarranz Imirizaldu, Juan José; Arteagoitia, Jose M.; Martínez de Pancorbo Gómez, María de los Angeles ; Atares, Begona; Bilbao, Miren J.; Ferrer, Isidro; Juste Jordán, Ramón A. (BioMed Central, 2010-10)Background: Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder in humans included in the group of Transmissible Spongiform Encephalopathies or prion diseases. The vast majority of sCJD cases are ... -
ADNmt: Caracterización de razas bovinas y ovinas autóctonas del País Vasco e identificación de especies animales de interés económico y forense
López Oceja, Andrés (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2016-11-14)El ADN mitocondrial (ADNmt) es un marcador molecular de gran interés en campos como la genética forense, la ecología o seguridad alimentaria, ya que contiene información esencial en diferentes campos de la genética animal, ... -
Association between nutrient intake related to the one-carbon metabolism and colorectal cancer risk: a case–control study in the Basque Country
Martín Fernández de Labastida, Silvia; Alegría Lertxundi, Iker; Martínez de Pancorbo Gómez, María de los Angeles ; Arroyo Izaga, Marta (Springer Nature, 2023)Purpose Epidemiologic evidence for the association between methyl-donor nutrient intake and colorectal cancer (CRC) risk remains inconclusive. We aimed to examine the relationship between intake of vitamins of the B ... -
Cell Patterning Technology on Polymethyl Methacrylate through Controlled Physicochemical and Biochemical Functionalization
Azuaje Hualde, Enrique ; Komen, Job; Alonso Cabrera, Juncal Anne ; Van den Berg, Albert; Martínez de Pancorbo Gómez, María de los Angeles ; Van der Meer, Andries D.; Benito López, Fernando ; Basabe Desmonts, Lourdes (MDPI, 2023-09-23)In recent years, innovative cell-based biosensing systems have been developed, showing impact in healthcare and life science research. Now, there is a need to design mass-production processes to enable their commercialization ... -
Combined micropatterning of cells, biosensors and nanomaterials: towards integrated microsystems for cell monitoring
El cultivo celular es una herramienta poderosa que permite estudiar los procesos celulares de una manera sencilla. Aunque los métodos convencionales cultivo han permitido obtener inmensurable conocimiento en muchísimas ... -
Continuous Monitoring of Cell Transfection Efficiency with Micropatterned Substrates
Azuaje Hualde, Enrique ; Rosique, Melania; Calatayud Sánchez, Alba ; Benito López, Fernando ; Basabe Desmonts, Lourdes ; Martínez de Pancorbo Gómez, María de los Angeles (Wiley, 2021-04-10)The effect of cell-cell contact on gene transfection is mainly unknown. Usually, transfection is carried out in batch cell cultures without control over cellular interactions, and efficiency analysis ... -
Cystic fibrosis severity modifier genes in patients from the north of the Iberian Peninsula and the Balearic Islands
Granizo Rodríguez, Eva (2023-06-23)Cystic fibrosis is the most common autosomal recessive rare disease in Caucasian populations. Despite the wide variety of mutations, patients with same mutations may present different clinical symptoms. This variability ... -
Descubrimiento de nuevas dianas terapéuticas en cáncer de mama basado en el análisis de metilación del ARNm.
Kleinbielen, Tamara Soledad (2022-04-07)N6-metiladenosina (m6A) es una de las modificaciones más abundante del ARNm presente en los organismos eucariotas. Distintos estudios han revelado que la modificación m6A está involucrada en la regulación de la mayoría de ... -
Design and Validation of a Process Based on Cationic Niosomes for Gene Delivery into Novel Urine-Derived Mesenchymal Stem Cells
Vado Ranedo, Yerai ; Puras Ochoa, Gustavo; Rosique, Melania; Martín Plágaro, César Augusto; Pedraz Muñoz, José Luis ; Jebari Benslaiman, Shifa; Martínez de Pancorbo Gómez, María de los Angeles ; Zarate Sesma, Jon ; Pérez de Nanclares Leal, Guiomar (MDPI, 2021-05-11)Background: Mesenchymal stem cells (MSCs) are stem cells present in adult tissues. They can be cultured, have great growth capacity, and can differentiate into several cell types. The isolation of urine-derived mesenchymal ... -
Diagenetic research of factors influencing the performance of biomolecular investigations of human skeletal remains from Spanish Civil War graves.
Raffone, Caterina (2023-03-09)During the Spanish Civil War and the posterior dictatorship, a huge number of people disappeared during the war or in episodes of repression. A large number of victims remain unidentified. One of the main limitations of ... -
Different Evolutionary History for Basque Diaspora Populations in USA and Argentina Unveiled by Mitochondrial DNA Analysis
Baeta Bafalluy, Miriam ; Núñez Domingo, Carolina; Cardoso Martín, Sergio; Palencia Madrid, Leire ; Piñeiro Hermida, Sergio; Arriba Barredo, Miren; Villanueva Millán, María Jesús; Martínez de Pancorbo Gómez, María de los Angeles (Public Library Science, 2015-12-14)The Basque Diaspora in Western USA and Argentina represents two populations which have maintained strong Basque cultural and social roots in a completely different geographic context. Hence, they provide an exceptional ... -
Distinct Correlations Between Lipogenic Gene Expression and Fatty Acid Composition of Subcutaneous Fat Among Cattle Breeds
Gamarra, David; Aldai Elkoro-Iribe, Noelia; Arakawa, Aisaku; Rodríguez Barrón, Luis Javier ; López Oceja, Andrés; Martínez de Pancorbo Gómez, María de los Angeles ; Taniguchi, Masaaki (Biomed Central, 2018-05-23)Background: The fatty acid (FA) composition of adipose tissue influences the nutritional quality of meat products. The unsaturation level of FAs is determined by fatty acid desaturases such as stearoyl- CoA desaturases ... -
DNA methylation epigenotypes in breast cancer molecular subtypes
García Bediaga, Naiara; Acha Sagredo, Amelia; Guerra, Isabel; Viguri, Amparo; Albaina, Carmen; Ruiz Díaz, Irune ; Rezola, Ricardo; Alberdi, María Jesús; Dopazo, Joaquín; Montaner, David; Renobales Scheifler, María Mercedes de; Fernández Fernández, Agustín; Field, John K.; Fraga, Mario F.; Liloglou, Liloglou; Martínez de Pancorbo Gómez, María de los Angeles (BioMed Central, 2010-09-29)Introduction: Identification of gene expression-based breast cancer subtypes is considered a critical means of prognostication. Genetic mutations along with epigenetic alterations contribute to gene-expression changes ... -
Entomología molecular: Diversidad y filogenia de dípteros de interés médico-legal y veterinario, y su aplicación en situaciones reales
Gil Arriortua, Maite Amalia (2016-12-20)El prerrequisito crítico en entomología médico-legal y veterinaria es la rápida y precisa identificación de la entomofauna recogida para estimar el periodo de actividad de los insectos (PAI), que se aproxima al intervalo ... -
Extracellular matrix protein microarray-based biosensor with single cell resolution: Integrin profiling and characterization of cell-biomaterial interactions
González Pujana, Ainhoa; Santos Vizcaíno, Edorta ; García Hernando, Maite ; Hernáez Estrada, Beatriz; Martínez de Pancorbo Gómez, María de los Angeles ; Benito López, Fernando ; Igartua Olaechea, Manuela ; Basabe Desmonts, Lourdes ; Hernández Martín, Rosa María (Elsevier, 2019-08-06)In the search of biomaterials that promote cell adhesion, it is crucial to explore the integrin-substrate dynamic interactions given in a certain cell type to design successful biofunctionalization strategies. Here, we use ... -
Food groups, diet quality and colorectal cancer risk in the Basque Country
Alegría Lertxundi, Iker; Aguirre Gómez, Carmelo; Bujanda Fernández de Pierola, Luis ; Fernández Pablos, Francisco Javier; Polo, Francisco; Ordovás, José María; Etxezarraga Zuluaga, María Carmen; Zabalza Estévez, Ignacio; Larzabal, Mikel; Portillo Villares, María Isabel; Martínez de Pancorbo Gómez, María de los Angeles ; García Etxebarria, Koldo; Rocandio Pablo, Ana María ; Arroyo Izaga, Marta (Baishideng Publishing Group Inc, 2020-07-28)BACKGROUND The results obtained to date concerning food groups, diet quality and colorectal cancer (CRC) risk vary according to criteria used and the study populations. AIM To study the relationships between food groups, ... -
Genetic characterization and gene expression associated with the fatty acid profile in cattle
Gamarra Fernández, David (2022-03-31)El sector agroalimentario es de gran importancia para la economía europea. La nueva política europea enreproducción animal está marcando una tendencia hacia sistemas de producción sostenibles utilizando recursosgenéticos ... -
Genetic Characterization of the Local Pirenaica Cattle for Parentage and Traceability Purposes
Gamarra, David; Taniguchi, Masaaki; Aldai Elkoro-Iribe, Noelia; Arakawa, Aisaku; López Oceja, Andrés; Martínez de Pancorbo Gómez, María de los Angeles (MDPI, 2020-09-05)Pirenaica is the most important autochthonous cattle breed within the Protected Geographic Indication (PGI) beef quality label in the Basque region, in northern Spain. The short tandem repeats (STRs) are powerful markers ... -
Gene–Diet Interactions in Colorectal Cancer: Survey Design, Instruments, Participants and Descriptive Data of a Case–Control Study in the Basque Country
Alegría Lertxundi, Iker; Aguirre Gómez, Carmelo; Bujanda Fernández de Pierola, Luis ; Fernández Pablos, Francisco Javier; Polo, Francisco; Ordovás, José María; Etxezarraga Zuluaga, María Carmen; Zabalza Estévez, Ignacio; Larzabal, Mikel; Portillo Villares, María Isabel; Martínez de Pancorbo Gómez, María de los Angeles ; Palencia Madrid, Leire ; García Etxebarria, Koldo; Rocandio Pablo, Ana María ; Arroyo Izaga, Marta (MDPI, 2020)Epidemiologic studies have revealed inconsistent evidence of gene-diet interaction in relation to colorectal cancer (CRC). The aim of this study was to analyze them in a sample of cases and controls from the population-based ...