Browsing by Author "Asensio, Juan L."

Now showing items 1-1 of 1

    • Thumbnail

      Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition 

      Bermejo, Iris A.; Usabiaga Gutiérrez, Imanol; Compañón, Ismael; Castro-López, Jorge; Insausti Beiro, Aran; Fernández González, José Andrés ORCID; Avenoza, Alberto; Busto, Jesús H.; Jiménez Barbero, Jesús ORCID; Asensio, Juan L.; Peregrina, Jesús M.; Jiménez Oses, Gonzalo; Hurtado Guerrero, Ramón; Cocinero Pérez, Emilio José; Corzana, Francisco (ACS, 2018-07-13)
      The tumor-associated carbohydrate Tn antigens include two variants, αGalNAc-O-Thr and αGalNAc-O-Ser. In solution, they exhibit dissimilar shapes and dynamics and bind differently to the same protein receptor. Here, we ...