Browsing by Author "Falzarano, Darryl"
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Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells
Icho, Simoun; Rujas Díez, Edurne; Muthuraman, Krithika; Tam, John; Liang, Huazhu; Landreth, Shelby; Liao, Mingmin; Falzarano, Darryl; Julien, Jean Philippe; Melnyk, Roman A. (American Society for Microbiology, 2022-07)An essential step in the infection life cycle of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the proteolytic activation of the viral spike (S) protein, which enables membrane fusion and entry into ...