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      Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease 

      Vilariño Güell, Carles; Zimprich, Alexander; Martinelli Boneschi, Filippo; Herculano, Bruno; Wang, Zhe; Matesanz, Fuencisla; Urcelay, Elena; Vandenbroeck, Koen; Leyva, Laura; Gris, Denis; Massaad, Charbel; Quandt, Jacqueline A.; Traboulsee, Anthony L.; Encarnacion, Mary; Bernales, Cecily Q.; Follett, Jordan; Yee, Irene M.; Criscuoli, Maria G.; Deutschlander, Angela; Reinthaler, Eva M.; Zrzavy, Tobias; Mascia, Elisabetta; Zauli, Andrea; Esposito, Federica; Alcina, Antonio; Izquierdo, Guillermo; Espino Paisan, Laura; Mena Lucía, Jorge; Rodríguez-Antigüedad Zarranz, Alfredo; Urbaneja Romero, Patricia; Ortega Pinazo, Jesús; Song, Weihong; Sadovnick, A. Dessa (Public Library Science 15(6) : (2019) // Article ID e1008180, 2019-06-06)
      Multiple sclerosis (MS) is an inflammatory disease of the central nervous system characterized by myelin loss and neuronal dysfunction. Although the majority of patients do not present familial aggregation, Mendelian forms ...