Browsing by Author "Battaglia, Luigi"

Now showing items 1-3 of 3

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      Gene delivery in the cornea: in vitro and ex vivo evaluation of solid lipid nanoparticle-based vectors 

      Vicente Pascual, Mónica; Albano, Andrea; Solinís Aspiazu, María Ángeles ORCID; Serpe, Loredana; Rodríguez Gascón, Alicia; Foglietta, Loredana; Muntoni, Elisabetta; Torrecilla, Josune; Del Pozo Rodríguez, Ana ORCID; Battaglia, Luigi (Future Medicine, 2018-08-01)
      Inflammation is a process that underlies sight-threatening ocular surface diseases, and gene supplementation with the plasmid that encodes for interleukin-10 (p- IL10) will allow the sustained de novo synthesis of the ...
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      mRNA-Based Nanomedicinal Products to Address Corneal Inflammation by Interleukin-10 Supplementation 

      Gómez Aguado, Itziar ORCID; Rodríguez Castejón, Julen ORCID; Beraza Millor, Marina ORCID; Vicente Pascual, Mónica; Rodríguez Gascón, Alicia; Garelli, Sara; Battaglia, Luigi; Del Pozo Rodríguez, Ana ORCID; Solinís Aspiazu, María Ángeles ORCID (MDPI, 2021-09-15)
      The anti-inflammatory cytokine Interleukin-10 (IL-10) is considered an efficient treatment for corneal inflammation, in spite of its short half-life and poor eye bioavailability. In the present work, mRNA-based nanomedicinal ...
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      Topical Administration of SLN-Based Gene Therapy for the Treatment of Corneal Inflammation by De Novo IL-10 Production 

      Vicente Pascual, Mónica; Gómez Aguado, Itziar ORCID; Rodríguez Castejón, Julen ORCID; Rodríguez Gascón, Alicia; Muntoni, Elisabetta; Battaglia, Luigi; Del Pozo Rodríguez, Ana ORCID; Solinís Aspiazu, María Ángeles ORCID (MDPI, 2020-06-23)
      One of the main challenges in gene therapy is the issue of delivery, and it is especially relevant for the success of gene therapy in the cornea. In the present work, eye drops containing biocompatible non-viral vectors ...