Browsing by Author "Franch Expósito, Sebastià"

Now showing items 1-3 of 3

    • Thumbnail

      Identification of a Novel Candidate Gene for Serrated Polyposis Syndrome Germline Predisposition by Performing Linkage Analysis Combined With Whole-Exome Sequencing 

      Toma, Claudio; Díaz Gay, Marcos; Soares de Lima, Yasmin; Arnau Collell, Coral; Franch Expósito, Sebastià; Muñoz, Jenifer; Overs, Bronwyn; Bonjoch, Laia; Carballal, Sabela; Ocaña, Teresa; Cuatrecasas, Miriam; Díaz de Bustamante, Aranzazu; Castells, Antoni; Bujanda Fernández de Pierola, Luis ORCID; Cubiella, Joaquín; Balaguer, Francesc; Rodríguez Alcalde, Daniel; Fullerton, Janice M.; Castellví-Bel, Sergi (Lippincott Williams & Wilkins, 2019-09-19)
      OBJECTIVES: Serrated polyposis syndrome (SPS) is a complex disorder with a high risk of colorectal cancer for which the germline factors remain largely unknown. Here, we combined whole-exome sequencing (WES) and linkage ...
    • Thumbnail

      Integrated Analysis of Germline and Tumor DNA Identifies New Candidate Genes Involved in Familial Colorectal Cancer 

      Díaz Gay, Marcos; Franch Expósito, Sebastià; Arnau Collell, Coral; Park, Solip; Supek, Fran; Muñoz, Jenifer; Bonjoch, Laia; Gratacós Mulleras, Anna; Sánchez Rojas, Paula A.; Esteban-Jurado, Clara; Ocaña, Teresa; Cuatrecasas, Miriam; Vila Casadesús, Maria; Lozano, Juan José; Parra, Genis; Laurie, Steve; Beltran, Sergi; EPICOLON Consortium; Castells, Antoni; Bujanda Fernández de Pierola, Luis ORCID; Cubiella, Joaquín; Balaguer, Francesc; Castellví-Bel, Sergi (MDPI, 2019-03-13)
      Colorectal cancer (CRC) shows aggregation in some families but no alterations in the known hereditary CRC genes. We aimed to identify new candidate genes which are potentially involved in germline predisposition to familial ...
    • Thumbnail

      Using linkage studies combined with whole-exome sequencing to identify novel candidate genes for familial colorectal cancer 

      Toma, Claudio; Díaz Gay, Marcos; Franch Expósito, Sebastià; Arnau Collell, Coral; Overs, Bronwyn; Muñoz, Jenifer; Bonjoch, Laia; Soares de Lima, Yasmin; Ocaña, Teresa; Cuatrecasas, Miriam; Castells, Antoni; Bujanda Fernández de Pierola, Luis ORCID; Balaguer, Francesc; Cubiella, Joaquín; Caldés, Trinidad; Fullerton, Janice M.; Castellví Bel, Sergi (Wiley, 2019-11)
      Colorectal cancer (CRC) is a complex disorder for which the majority of the underlying germline predisposition factors remain still unidentified. Here, we combined whole-exome sequencing (WES) and linkage analysis in ...