Now showing items 1-2 of 2

    • Thumbnail

      4E10 anti-mper antigorputzaren optimizazioa: CDR-H3 begiztaren aldaketen ebaluazioa 

      Insausti González, Sara (2016-04-28)
      VIH-ren fusioa inhibitzeko gai diren antigorputzen adierazpena eta purifikazioa bakterietan. Funtzionaltasunaren analisia (ITC eta pseudobirusak erabiliz egindako neutralizazio saioak) eta optimizazioa.
    • Thumbnail

      Molecular Recognition of the Native HIV-1 MPER Revealed by STED Microscopy of Single Virions 

      Carravilla Palomanes, Pablo; Chojnacki, Jakub; Rujas Díez, Edurne; Insausti González, Sara; Largo Pereda, Eneko; Waithe, Dominic; Apellaniz Unzalu, Beatriz; Sicard, Taylor; Julien, Jean Philippe; Eggeling, Christian; Nieva Escandón, José Luis (Springer, 2019-01-08)
      Antibodies against the Membrane-Proximal External Region (MPER) of the Env gp41 subunit neutralize HIV-1 with exceptional breadth and potency. Due to the lack of knowledge on the MPER native structure and accessibility, ...