Browsing by Author "Lezcano-García, Elena"

Now showing items 1-1 of 1

    • Thumbnail

      Exploring Genetic Factors Involved in Huntington Disease Age of Onset: E2F2 as a New Potential Modifier Gene 

      Valcárcel Ocete, Leire; Alkorta Aranburu, Gorka; Iriondo Orensanz, Mikel ORCID; Fullaondo Elordui-Zapaterieche, Asier ORCID; García-Barcina, María; Fernández-García, José Manuel; Lezcano-García, Elena; Losada-Domingo, José María; Ruiz-Ojeda, Javier; Álvarez de Arcaya, Amaia; Pérez- Ramos, José María; Roos, Raymund A. C.; Nielsen, Jørgen E.; Saft, Carsten; REGISTRY investigators of the European Huntington's Disease Network; Zubiaga Elordieta, Ana María ORCID; Aguirre Escobal, Ana Isabel ORCID (Public Library Science, 2015-07-06)
      Age of onset (AO) of Huntington disease (HD) is mainly determined by the length of the CAG repeat expansion (CAGexp) in exon 1 of the HTT gene. Additional genetic variation has been suggested to contribute to AO, although ...