BackBrowsing by Author "Valcárcel Jiménez, Lorea"
Now showing items 1-3 of 3
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Integrative Analysis of Transcriptomics and Clinical Data Uncovers the Tumor- Suppressive Activity of MITF in Prostate Cancer
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Carracedo Pérez, Arkaitz
; (Nature Publishing Group, 2018-10-11)
The dysregulation of gene expression is an enabling hallmark of cancer. Computational analysis of transcriptomics data from human cancer specimens, complemented with exhaustive clinical annotation, provides an opportunity ... -
Targeting PML in triple negative breast cancer elicits growth suppression and senescence
Arreal López, Leire; Piva, Marco; Fernández Ruiz, Sonia; Revandkar, Ajinkya; Schaub Clerigué, Ariane; Villanueva, Josep; Zabala Letona, Amaia; Pujana Vaquerizo, Mikel; Astobiza Pérez, Ianire; Cortázar, Ana Rosa; Hermanova, Ivana; Bozal Basterra, Laura; Arruabarrena Aristorena, Amaia; Crespo, Jana R.; Valcárcel Jiménez, Lorea; Zuñiga García, Patricia; Canals, Francesc; Torrano Moya, Verónica; Barrio Olano, María Rosa; Sutherland, James D.; Alimonti, Andrea; Martín Martín, Natalia; Carracedo Pérez, Arkaitz (Nature, 2020-04)
Oncogene addiction postulates that the survival and growth of certain tumor cells is dependent upon the activity of one oncogene, despite their multiple genetic and epigenetic abnormalities. This phenomenon provides a ... -
Transcriptional control of prostate cancer metabolism
(2017-12-18)La transformación y la progresión tumoral van acompañados de cambios metabólicos. Los principales co-reguladores metabólicos son capaces de orquestar la modulación de múltiples rutas metabólicas a través de la regulación ...