Now showing items 1-3 of 3

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      GAT-3 Dysfunction Generates Tonic Inhibition in Exter nal Globus Pallidus Neurons in Parkinsonian Rodents 

      Chazalon, Marine; Paredes Rodríguez, Elena; Morin, Stéphanie; Martinez, Audrey; Cristóvão-Ferreira, Sofia; Vaz, Sandra; Sebastiao, Ana; Panatier, Aude; Boué-Grabot, Eric; Miguélez Palomo, Cristina; Baufreton, Jérôme (Cell Press, 2018-05-08)
      The external globus pallidus (GP) is a key GABAergic hub in the basal ganglia (BG) circuitry, a neuronal network involved in motor control. In Parkinson's disease (PD), the rate and pattern of activity of GP neurons are ...
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      Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep 

      Hayat, Hanna; Regev, Noa; Matosevich, Noa; Sales, Anna; Paredes Rodríguez, Elena; Krom, Aaron J.; Berg, Lottem; Li, Yong; Lavigne, Marina; Kremer, Eric J.; Yizhar, Ofer; Pickering, Anthony E.; Nirl, Yuval (American Association for the Advancement of Science, 2020-04-08)
      A defining feature of sleep is reduced responsiveness to external stimuli, but the mechanisms mediating sensory-evoked arousal remain unclear. We hypothesized that reduced locus coeruleus (LC) norepinephrine (NE) activity ...
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      Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure 

      De Salas Quiroga, Adán; García Rincón, Daniel; Gómez Domínguez, Daniel; Valero, Manuel; Simón Sánchez, Samuel; Paraíso Luna, Juan; Aguareles, José; Pujadas, Mitona; Muguruza Millán, Carolina; Callado Hernando, Luis Felipe; Lutz, Beat; Guzmán, Manuel; Menéndez de la Prida, Liset; Galve Roperh, Ismael (Nature, 2020-04)
      Prenatal exposure to Delta(9)-tetrahydrocannabinol (THC), the most prominent active constituent of cannabis, alters neurodevelopmental plasticity with a long-term functional impact on adult offspring. Specifically, THC ...