Now showing items 1-10 of 10

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      Cholangiocarcinoma 2020: the next horizon in mechanisms and management 

      Bañales Asurmendi, Jesús María; García Marín, Jose Juan; Lamarca, Angela; Rodrigues, Pedro M.; Khan, Shahid A.; Roberts, Lewis R.; Cardinale, Vincenzo; Carpino, Guido; Andersen, Jesper B.; Braconi, Chiara; Calvisi, Diego; Perugorria Montiel, María Jesús; Fabris, Luca; Boulter, Luke; Macias, Rocio I. R.; Gaudio, Eugenio; Alvaro, Domenico; Gradilone, Sergio A.; Strazzabosco, Mario; Marzioni, Marco; Coulouarn, Cédric; Fouassier, Laura; Raggi, Chiara; Invernizzi, Pietro; Mertens, Joachim C.; Moncsek, Anja; Rizvi, Sumera; Heimbach, Julie; Groot Koerkamp, Bas; Bruix, Jordi; Forner, Alejandro; Bridgewater, John; Valle, Juan W.; Gores, Gregory J. (Springer Nature, 2020-06-30)
      [EN] Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant tumours that can arise at any point of the biliary tree. Their incidence is increasing globally, currently accounting for ~15% ...
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      Development and external validation of a faecal immunochemical test-based prediction model for colorectal cancer detection in symptomatic patients 

      Cubiella, Joaquín; Vega, Pablo; Salve, María; Díaz-Ondina, Marta; Alves, Maria Teresa; Quintero, Enrique; Álvarez-Sánchez, Victoria; Fernández-Bañares, Fernando; Boadas, Jaume; Campo, Rafel; Bujanda Fernández de Pierola, Luis; Clofent, Joan; Ferrandez, Ángel; Torrealba, Leyanira; Piñol, Virginia; Rodríguez-Alcalde, Daniel; Hernández, Vicent; Fernández-Seara, Javier; COLONPREDICT study investigators (Biomed Central, 2016-08-31)
      Background: Risk prediction models for colorectal cancer (CRC) detection in symptomatic patients based on available biomarkers may improve CRC diagnosis. Our aim was to develop, compare with the NICE referral criteria and ...
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      Influence of MUC5B gene on antisynthetase syndrome 

      López Mejías, Raquel; Remuzgo Martínez, Sara; Genre, Fernanda; Pulito Cueto, Verónica; Fernández Rozas, Sonia M.; Llorca, Javier; Iturbe Fernández, David; Mora Cuesta, Víctor M.; Ortego Centeno, Norberto; Pérez Gómez, Nair; Mera Varela, Antonio; Martínez Barrio, Julia; López Longo, Francisco Javier; Mijares, Verónica; Lera Gómez, Leticia; Usetti, María Piedad; Laporta, Rosalía; Pérez, Virginia; De Pablo Gafas, Alicia; Alfranca González, María Aránzazu; Calvo Alén, Jaime; Romero Bueno, Fredeswinda; Sanchez Pernaute, Olga; Nuno, Laura; Bonilla, Gema; Balsa, Alejandro; Hernández González, Fernanda; Grafia, Ignacio; Prieto González, Sergio; Narváez, Javier; Trallero Araguas, Ernesto; Selva O’Callaghan, Albert; Gualillo, Oreste; Castañeda, Santos; Cavagna, Lorenzo; Cifrian, José M.; González Gay, Miguel A. (Nature, 2020-01-29)
      MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ...
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      Influence of MUC5B gene on antisynthetase syndrome 

      López Mejías, Raquel; Remuzgo Martínez, Sara; Genre, Fernanda; Pulito Cueto, Verónica; Fernández Rozas, Sonia M.; Llorca, Javier; Iturbe Fernández, David; Mora Cuesta, Víctor M.; Ortego Centeno, Norberto; Pérez Gómez, Nair; Mera Varela, Antonio; Martínez Barrio, Julia; López Longo, Francisco Javier; Mijares, Verónica; Lera Gómez, Leticia; Usetti, María Piedad; Laporta, Rosalía; Pérez, Virginia; De Pablo Gafas, Alicia; Alfranca González, María Aránzazu; Calvo Alén, Jaime; Romero Bueno, Fredeswinda; Sánchez Pernaute, Olga; Nuño Nuño, Laura; Bonilla, Gema; Balsa, Alejandro; Hernández González, Fernanda; Grafia, Ignacio; Prieto González, Sergio; Narvaez, Javier; Trallero Araguas, Ernesto; Selva O’Callaghan, Albert; Gualillo, Oreste; Castañeda, Santos; Cavagna, Lorenzo; Cifrian, José M.; González Gay, Miguel A. (Nature, 2020-01-29)
      MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ...
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      Mediterranean diet and quality of life: Baseline cross-sectional analysis of the PREDIMED-PLUS trial 

      PREDIMED-PLUS Study Investigators; Arós Borau, Luis Fernando (Public Libray fo Science, 2018-06-18)
      We assessed if a 17-item score capturing adherence to a traditional Mediterranean diet (MedDiet) was associated with better health-related quality of life among older Spanish men and women with overweight or obesity harboring ...
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      Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis 

      Lapitz Dambolenea, Ainhoa; Arbelaiz Cossio, Ander; O’Rourke, Colm J.; Lavín, José L.; Casta, Adelaida La; Ibarra, Cesar; Jimeno, Juan P.; Santos Laso, Alvaro; Izquierdo-Sanchez, Laura; Krawczyk, Marcin; Perugorria Montiel, María Jesús; Jiménez Agüero, Raúl; Sanchez-Campos, Alberto; Riaño Fernández, Ioana; Gónzalez, Esperanza; Lammert, Frank; Marzioni, Marco; Rodríguez Macías, Rocío Isabel; García Marín, Jose Juan; Karlsen, Tom H.; Bujanda Fernández de Pierola, Luis; Falcón Pérez, Juan Manuel; Andersen, Jesper B.; Aransay Bañares, Ana María; Rodrigues, Pedro M.; Bañales Asurmendi, Jesús María (MDPI, 2020-03-14)
      Cholangiocarcinoma (CCA) comprises a group of heterogeneous biliary cancers with dismal prognosis. The etiologies of most CCAs are unknown, but primary sclerosing cholangitis (PSC) is a risk factor. Non-invasive diagnosis ...
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      Serum Metabolites as Diagnostic Biomarkers for Cholangiocarcinoma, Hepatocellular Carcinoma, and Primary Sclerosing Cholangitis 

      Bañales Asurmendi, Jesús María; Iñarrairaegui, Mercedes; Arbelaiz Cossio, Ander; Milkiewicz, Piotr; Muntané, Jordi; Muñoz Bellvis, Luis; La Casta, Adelaida; Gonzaz, Luis M.; Arretxe Oliden, Enara; Alonso, Cristina; Martínez Arranz, Ibon; Lapitz Dambolenea, Ainhoa; Santos Laso, Alvaro; Avila, Matias A.; Martínez Chantar, María Luz; Bujanda Fernández de Pierola, Luis; García Marín, Jose Juan; Sangro, Bruno; Rodríguez Macías, Rocío Isabel (Wiley, 2019-08)
      Early and differential diagnosis of intrahepatic cholangiocarcinoma (iCCA) and hepatocellular carcinoma (HCC) by noninvasive methods represents a current clinical challenge. The analysis of low-molecular-weight metabolites ...
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      Symptom or faecal immunochemical test based referral criteria for colorectal cancer detection in symptomatic patients: a diagnostic tests study 

      Herrero, Jesús-Miguel; Vega, Pablo; Salve, María; Bujanda Fernández de Pierola, Luis; Cubiella, Joaquín (Biomed Central, 2018-10-25)
      BackgroundSymptom based referral criteria for colorectal cancer (CRC) detection are the cornerstone of the strategy to improve prognosis in CRC. In 2017, the National Institute for Health and Care Excellence (NICE) updated ...
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      The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome 

      Marcos Delgado, Alba; Fernández Villa, Tania; Martínez González, Miguel Ángel; Salas Salvadó, Jordi; Corella, Dolores; Castañer, Olga; Martínez, J. Alfredo; Alonso Gómez, Ángel María; Wärnberg, Julia; Vioque, Jesús; Romaguera, Dora; López Miranda, José; Estruch, Ramón; Tinahones, Francisco J; Lapetra, José; Serra Majem, LLuís; García Molina, Laura; Tur, Josep A.; De Paz, José Antonio; Pintó, Xavier; Delgado Rodríguez, Miguel; Matía Martín, Pilar; Vidal, Josep; Vázquez, Clotilde; Daimiel, Lidia; Ros, Emilio; Babio, Nancy; Giménez Alba, Ignacio M; Toledo, Estefanía; Zomeño, María Dolores; Zulet, M. Ángeles; Vaquero Luna, Jessica; Pérez López, Jessica; Pastor Morel, Ana; Galmes Panades, Aina María; García Ríos, Antonio; Casas, Rosa; Bernal López, María Rosa; Santos Lozano, José Manuel; Becerra Tomás, Nerea; Ortega Azorín, Carolina; Vázquez Ruiz, Zenaida; Pérez Vega, Karla Alejandra; Abete, Itziar; Sorto Sánchez, Carolina; Palau Galindo, Antoni; Galilea Zabalza, Iñigo; Muñoz Martínez, Júlia; Martín, Vicente (MDPI, 2020-05-25)
      The main objective of this study was to examine the relationship between the level of physical activity (PA) and the degree of obesity with health-related quality of life (HRQoL) in individuals with metabolic syndrome ...
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      The MLH1 c.1852_1853delinsGC (p.K618A) Variant in Colorectal Cancer: Genetic Association Study in 18,723 Individuals 

      Abulí, Anna; Bujanda Fernández de Pierola, Luis; Mun, Jenifer; Buch, Stephan; Schafmayer, Clemens; Maiorana, Maria Valeria; Veneroni, Silvia; Van Wezel, Tom; Liu, Tao; Westers, Helga; Esteban-Jurado, Clara; Ocan, Teresa; Pique, Josep M.; Andreu, Montserrat; Jover, Rodrigo; Carracedo, Angel; Xicola, Rosa M.; Llor, Xavier; Castells, Antoni; The EPICOLON Consortium; Dunlop15, Malcolm; Hofstra, Robert; Lindblom, Annika; Wijnen, Juul; Peterlongo, Paolo; Hampe, Jochen; Ruiz- Ponte, Clara; Castellví-Bel, Sergi (Public Library Science, 2014-04-17)
      Colorectal cancer is one of the most frequent neoplasms and an important cause of mortality in the developed world. Mendelian syndromes account for about 5% of the total burden of CRC, being Lynch syndrome and familial ...