dc.contributor.author | Sánchez Sánchez, Ana Belén | |
dc.contributor.author | Pomposo Alonso, José Adolfo | |
dc.date.accessioned | 2016-05-10T10:44:18Z | |
dc.date.available | 2016-05-10T10:44:18Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Journal of nanomaterials 2015 : (2015) // Article ID723492 | es |
dc.identifier.issn | 1687-4110 | |
dc.identifier.issn | 1687-4129 | |
dc.identifier.uri | http://hdl.handle.net/10810/18209 | |
dc.description.abstract | Single-chain technology (SCT) allows the transformation of individual polymer chains to folded/collapsed unimolecular soft nanoparticles. In this work we contribute to the enlargement of the SCT toolbox by demonstrating the efficient synthesis of single-chain polymer nanoparticles (SCNPs) via intrachain amide formation. In particular, we exploit cross-linking between active methylene groups and isocyanate moieties as powerful "click" chemistry driving force for SCNP construction. By employing poly(methyl methacrylate)- (PMMA-) based copolymers bearing beta-ketoester units distributed randomly along the copolymer chains and bifunctional isocyanate cross-linkers, SCNPs were successfully synthesized at r.t. under appropriate reaction conditions. Characterization of the resulting SCNPs was carried out by means of a combination of techniques including size exclusion chromatography (SEC), infrared (IR) spectroscopy, proton nuclear magnetic resonance (H-1 NMR) spectroscopy, dynamic light scattering (DLS), and elemental analysis (EA). | es |
dc.description.sponsorship | Financial support from Projects MAT2012-31088 (MINE-CO), T-654-13 (GV), and S-PE13UN034 (GV) is acknowledged. Ana Sanchez-Sanchez thanks the Ph.D. grant support of Basque Government. | es |
dc.language.iso | eng | es |
dc.publisher | Hindawi Publishing | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | intramolecular cross-linking | es |
dc.subject | click chemistry | es |
dc.subject | polistyrene nanoparticles | es |
dc.subject | disordered proteins | es |
dc.subject | collapse | es |
dc.subject | covalent | es |
dc.subject | macromolecules | es |
dc.subject | noncovalent | es |
dc.subject | route | es |
dc.subject | bondis | es |
dc.title | Efficient Synthesis of Single-Chain Polymer Nanoparticles via Amide Formation | es |
dc.type | info:eu-repo/semantics/article | es |
dc.rights.holder | © 2015 A. Sanchez-Sanchez and J. A. Pomposo. This is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is
properly cited. | es |
dc.relation.publisherversion | http://www.hindawi.com/journals/jnm/2015/723492/abs/ | es |
dc.identifier.doi | 10.1155/2015/723492 | |
dc.departamentoes | Física de materiales | es_ES |
dc.departamentoeu | Materialen fisika | es_ES |
dc.subject.categoria | MATERIALS SCIENCE | |