Browsing ACHUCARRO by Author "Abiega Etxabe, Oihane"

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      Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis 

      Sierra Saavedra, Amanda; Abiega Etxabe, Oihane; Shahraz, Anahita; Neumann, Harald (Frontiers Research Foundation, 2013-01)
      Microglia are the resident brain macrophages and they have been traditionally studied as orchestrators of the brain inflammatory response during infections and disease. In addition, microglia has a more benign, less explored ...
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      Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling 

      Abiega Etxabe, Oihane; Beccari Galeano, Marlene Soledad; Diaz-Aparicio, Irune; Nadjar, Agnes; Layé, Sophie; Leyrolle, Quentin; Gómez-Nicola, Diego; Domercq García, María ORCID; Pérez-Samartín, Alberto; Sánchez-Zafra, Víctor; Paris Guerrero, Ignacio; Valero Gómez-Lobo, Jorge; Savage, Julie C.; Hui, Chin-Wai; Tremblay, Marie-Ève; Deudero, Juan J. P.; Brewster, Amy L.; Anderson, Anne E.; Zaldumbide Dueñas, Laura; Galbarriatu, Lara; Marinas, Ainhoa; Vivanco Ruiz, María del Mar; Matute Almau, Carlos José; Maletic-Savatic, Mirjana; Encinas Pérez, Juan Manuel; Sierra Saavedra, Amanda (2016)
      Phagocytosis by microglia is tightly coupled to apoptosis, swiftly removing apoptotic cells and actively maintaining tissue homeostasis, but the neuronal hyperactivity associated with epilepsy disrupts the ATP gradients ...