Now showing items 1-8 of 8

    • Thumbnail

      Behavioral profile of adults with Prader-Willi syndrome : correlations with individual and environmental variables 

      Jauregu Picabea, Joseba; Laurier, Virginie; Copet, Pierre; Tauber, Maithé; Thuilleaux, Denise (BioMed Central, 2013)
      Background: Maladaptive behavior has been reported as a phenotypical feature in Prader–Willi syndrome (PWS). It severely limits social adaptation and the quality of life of children and adults with the syndrome. Different ...
    • Thumbnail

      Classification of neocortical interneurons using affinity propagation 

      Santana Hermida, Roberto; McGarry, Laura M.; Bielza, Concha; Larrañaga, Pedro; Yuste, Rafel (Frontiers Reseach Foundation, 2013-12)
      In spite of over a century of research on cortical circuits, it is still unknown how many classes of cortical neurons exist. Neuronal classification has been a difficult problem because it is unclear what a neuronal cell ...
    • Thumbnail

      Epitope mapping of antibodies to alpha-synuclein in LRRK2 mutation carriers, idiopathic Parkinson disease patients, and healthy controls 

      Alvarez-Castelao, Beatriz; Gorostidi, Ana; Ruíz-Martínez, Javier; López de Munain Arregui, Adolfo José; Castaño, José G. (Frontiers Research Foundation, 2014-07-15)
      Alpha-synuclein (Snca) plays a major role in Parkinson disease (PD). Circulating anti-Snca antibodies has been described in PD patients and healthy controls, but they have been poorly characterized. This study was designed ...
    • Thumbnail

      Increased opioid dependence in a mouse model of panic disorder 

      Gallego, Xabier; Murtra, Patricia; Zamalloa Echevarría, Teresa; Canals, Josep Maria; Pineda Ortíz, Joseba Gotzon; Amador Arjona, Alejandro; Maldonado, Rafael; Dierssen, Mara (Frontiers Research Fundation, 2010-02-22)
      [EN] Panic disorder is a highly prevalent neuropsychiatric disorder that shows co-occurrence with substance abuse. Here, we demonstrate that TrkC, the high-affinity receptor for neurotrophin-3, is a key molecule involved ...
    • Thumbnail

      Interaction between the 5-HT system and the basal ganglia: functional implication and therapeutic perspective in Parkinson's disease 

      Miguélez Palomo, Cristina; Morera Herreras, Teresa; Torrecilla Sesma, María; Ruiz-Ortega, José Ángel; Ugedo Urruela, Luisa (Frontiers Research Foundation, 2014-03-17)
      The neurotransmitter serotonin (5-HT) has a multifaceted function in the modulation of information processing through the activation of multiple receptor families, including G-protein-coupled receptor subtypes (5-HT1, ...
    • Thumbnail

      Muscle wasting in myotonic dystrophies: a model of premature aging 

      Mateos Aierdi, Alba Judith; Goicoechea, María; Aiastui, Ana; Fernández-Torrón, Roberto; García-Puga, Mikel; Matheu Fernández, Ander; López de Munain Arregui, Adolfo José (Frontiers Research Foundation, 2015-07-09)
      Myotonic dystrophy type 1 (DM1 or Steinert's disease) and type 2 (DM2) are multisystem disorders of genetic origin. Progressive muscular weakness, atrophy and myotonia are the most prominent neuromuscular features of these ...
    • Thumbnail

      Prosocial behavior and gender 

      Espinosa Alejos, María Paz; Kovarik, Jaromir (Frontiers Research Foundation, 2015-04-14)
      This study revisits different experimental data sets that explore social behavior in economic games and uncovers that many treatment effects may be gender-specific. In general, men and women do not differ in "neutral" ...
    • Thumbnail

      The role of acetaldehyde in the increased acceptance of ethanol after prenatal ethanol exposure 

      Gaztañaga Echeverria, Mirari; Angulo-Alcalde, Asier; Spear, Norman E.; Chotro, M. Gabriela (Merce Correa, Jaume I University, Spain, 2017-01-31)
      Recent studies show that acetaldehyde, the first metabolite in the oxidation of ethanol, can be responsible for both, the appetitive and the aversive effects produced by ethanol intoxication. More specifically, it has been ...