Now showing items 1-3 of 3

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      Glycan structures and their interactions with proteins. A NMR view 

      Gimeno, Ana; Valverde, Pablo; Ardá, Ana; Jiménez Barbero, Jesús (Elsevier, 2019-12)
      Carbohydrate molecules are essential actors in key biological events, being involved as recognition points for cell-cell and cell-matrix interactions related to health and disease. Despite outstanding advances in cryoEM, ...
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      Glycans in drug discovery 

      Valverde, Pablo; Ardá, Ana; Reichardt, Niels Christian; Jiménez Barbero, Jesús; Gimeno, Ana (Royal Soc Chemistry, 2019-07-26)
      Glycans are key players in many biological processes. They are essential for protein folding and stability and act as recognition elements in cell-cell and cell-matrix interactions. Thus, being at the heart of medically ...
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      Synthetic, Zwitterionic Sp1 Oligosaccharides Adopt a Helical Structure Crucial for Antibody Interaction 

      Zhang, Qingju; Gimeno, Ana; Santana, Darielys; Wang, Zhen; Valdés Balbín, Yury; Rodríguez Noda, Laura M.; Hansen, Thomas; Kong, Li; Shen, Mengjie; Overkleeft, Herman S.; Verez Bencomo, Vicente; Van der Marel, Gijsbert A.; Jiménez Barbero, Jesús; Chiodo, Fabrizio; Codee, Jeroen D. C. (American Chemical Society, 2019-08-28)
      The zwitterionic Streptococcus pneumoniae serotype 1 polysaccharide (Sp1) is an important anchor point for our immune system to act against streptococcal infections. Antibodies can recognize Sp1 saccharides, and it has ...