Now showing items 1-1 of 1

    • Thumbnail

      Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells 

      Apraiz García, Aintzane ORCID; Idkowiak-Baldys, Jolanta K.; Boyano López, María Dolores ORCID; Pérez-Yarza Pérez-Irezabal, Gorka ORCID; Hannun, Yusuf A.; Asumendi Mallea, Aintzane ORCID (BioMed Central, 2011-10-07)
      Background -- N-(4-hydroxyphenyl)retinamide (4-HPR, fenretinide) is a synthetic retinoid with potent pro-apoptotic activity against several types of cancer, but little is known regarding mechanisms leading to chemoresistance. ...