Now showing items 1-4 of 4

    • Thumbnail

      Identification and characterization of miRNAs in spleens of sheep subjected to repetitive vaccination 

      Varela Martínez, Endika ORCID; Bilbao Arribas, Martín; Abendaño Carbajo, Naiara ORCID; Asín, Javier; Pérez, Marta Maria; Luján, Lluís; Jugo Orrantia, Begoña Marina ORCID (Nature, 2023-04)
      Accumulative evidence has shown that short non-coding RNAs such as miRNAs can regulate the innate and adaptive immune responses. Aluminium hydroxide is a commonly used adjuvant in human and veterinary vaccines. Despite its ...
    • Thumbnail

      Identification of sheep lncRNAs related to the immune response to vaccines and aluminium adjuvants 

      Bilbao Arribas, Martín; Varela Martínez, Endika ORCID; Abendaño Carbajo, Naiara ORCID; De Andrés, Damián; Luján, Lluís; Jugo Orrantia, Begoña Marina ORCID (BMC, 2021-10-28)
      [EN]Background Long non-coding RNAs (lncRNAs) are involved in several immune processes, including the immune response to vaccination, but most of them remain uncharacterised in livestock species. The mechanism of action ...
    • Thumbnail

      Molecular Signature of Aluminum Hydroxide Adjuvant in Ovine PBMCs by Integrated mRNA and microRNA Transcriptome Sequencing 

      Varela Martínez, Endika ORCID; Abendaño Carbajo, Naiara ORCID; Asín, Javier; Sistiaga Poveda, Maialen; Pérez, Marta Maria; Reina, Ramsés; De Andrés, Damián; Luján, Lluís; Jugo Orrantia, Begoña Marina ORCID (Frontiers Media, 2018-10-23)
      There have been few in vivo studies on the effect of aluminum hydroxide adjuvant and its influence on the immune response to vaccination. In this study, lambs received a parallel subcutaneous treatment with either commercial ...
    • Thumbnail

      Whole Transcriptome Approach to Evaluate the Effect of Aluminium Hydroxide in Ovine Encephalon 

      Varela Martínez, Endika ORCID; Bilbao Arribas, Martín; Abendaño Carbajo, Naiara ORCID; Asín, Javier; Pérez, Marta Maria; De Andrés, Damián; Luján, Lluís; Jugo Orrantia, Begoña Marina ORCID (Nature, 2020-09-17)
      Aluminium hydroxide adjuvants are crucial for livestock and human vaccines. Few studies have analysed their effect on the central nervous system in vivo. In this work, lambs received three different treatments of parallel ...