Browsing Artículos by Author "Luján, Lluís"
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Identification and characterization of miRNAs in spleens of sheep subjected to repetitive vaccination
Varela Martínez, Endika ; Bilbao Arribas, Martín; Abendaño Carbajo, Naiara ; Asín, Javier; Pérez, Marta Maria; Luján, Lluís; Jugo Orrantia, Begoña Marina (Nature, 2023-04)Accumulative evidence has shown that short non-coding RNAs such as miRNAs can regulate the innate and adaptive immune responses. Aluminium hydroxide is a commonly used adjuvant in human and veterinary vaccines. Despite its ... -
Identification of sheep lncRNAs related to the immune response to vaccines and aluminium adjuvants
Bilbao Arribas, Martín; Varela Martínez, Endika ; Abendaño Carbajo, Naiara ; De Andrés, Damián; Luján, Lluís; Jugo Orrantia, Begoña Marina (BMC, 2021-10-28)[EN]Background Long non-coding RNAs (lncRNAs) are involved in several immune processes, including the immune response to vaccination, but most of them remain uncharacterised in livestock species. The mechanism of action ... -
Molecular Signature of Aluminum Hydroxide Adjuvant in Ovine PBMCs by Integrated mRNA and microRNA Transcriptome Sequencing
Varela Martínez, Endika ; Abendaño Carbajo, Naiara ; Asín, Javier; Sistiaga Poveda, Maialen; Pérez, Marta Maria; Reina, Ramsés; De Andrés, Damián; Luján, Lluís; Jugo Orrantia, Begoña Marina (Frontiers Media, 2018-10-23)There have been few in vivo studies on the effect of aluminum hydroxide adjuvant and its influence on the immune response to vaccination. In this study, lambs received a parallel subcutaneous treatment with either commercial ... -
Whole Transcriptome Approach to Evaluate the Effect of Aluminium Hydroxide in Ovine Encephalon
Varela Martínez, Endika ; Bilbao Arribas, Martín; Abendaño Carbajo, Naiara ; Asín, Javier; Pérez, Marta Maria; De Andrés, Damián; Luján, Lluís; Jugo Orrantia, Begoña Marina (Nature, 2020-09-17)Aluminium hydroxide adjuvants are crucial for livestock and human vaccines. Few studies have analysed their effect on the central nervous system in vivo. In this work, lambs received three different treatments of parallel ...