Browsing Artículos by Author "Valcarcel, María"
Now showing items 1-3 of 3
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Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18
Salado, Clarisa; Olaso Montero, Elvira; Gallot, Natalia; Valcarcel, María; Egilegor, Eider; Mendoza, Lorea; Vidal Vanaclocha, Fernando (BioMed Central, 2011-05)Background: Implantation and growth of metastatic cancer cells at distant organs is promoted by inflammation-dependent mechanisms. A hepatic melanoma metastasis model where a majority of metastases are generated via ... -
Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis
Valcarcel, María; Arteta Ruiz, Beatriz ; Jaureguibeitia, Arrate; Lopategi Martínez, Aritz; Martínez, Iñigo; Mendoza, Lorea; Muruzabal, Francisco J.; Salado, Clarisa; Vidal Vanaclocha, Fernando (BioMed Central, 2008-10)Background: The recruitment of vascular stromal and endothelial cells is an early event occurring during cancer cell growth at premetastatic niches, but how the microenvironment created by the initial three-dimensional ... -
Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
Valcarcel, María; Mendoza, Lorea; Hernández, José Julio; Carrascal, Teresa; Salado, Clarisa; Crende Arruabarrena, Olatz ; Vidal Vanaclocha, Fernando (BioMed Central, 2011-08)Background: Human melanoma frequently colonizes bone marrow (BM) since its earliest stage of systemic dissemination, prior to clinical metastasis occurrence. However, how melanoma cell adhesion and proliferation mechanisms ...