Browsing Artículos by Author "Witton, J."
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Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease
Rodríguez Arellano, José Julio; Witton, J.; Olabarria, M.; Noristani, H.N.; Verkhratsky, Alexei (Nature Publishing Group, 2010-01)The formation of cerebral senile plaques composed of amyloid beta peptide (A beta) is a fundamental feature of Alzheimer's disease (AD). Glial cells and more specifically microglia become reactive in the presence of A beta. ...