BackBrowsing Artículos by Author "Zaldumbide Dueñas, Laura"
Now showing items 1-6 of 6
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Dual-Specificity Phosphatases in Neuroblastoma Cell Growth and Differentiation
Nunes Xavier, Caroline E.; Zaldumbide Dueñas, Laura; Aurtenetxe, Olaia; López Almaraz, Ricardo; López Fernández de Villaverde, José Ignacio
; Pulido Murillo, Rafael (MDPI, 2019-03-01)
Dual-specificity phosphatases (DUSPs) are important regulators of neuronal cell growth and differentiation by targeting proteins essential to neuronal survival in signaling pathways, among which the MAP kinases (MAPKs) ... -
Identification and Functional Analysis of a Novel CTNNB1 Mutation in Pediatric Medulloblastoma
(MDPI, 2022-01-14)Medulloblastoma is the primary malignant tumor of the Central Nervous System (CNS) most common in pediatrics. We present here, the histological, molecular, and functional analysis of a cohort of 88 pediatric medulloblastoma ... -
Identification of germline cancer predisposition variants in pediatric sarcoma patients from somatic tumor testing
(Nature, 2023-02)Genetic predisposition is an important risk factor for cancer in children and adolescents but detailed associations of individual genetic mutations to childhood cancer are still under intense investigation. Among pediatric ... -
Protein tyrosine phosphatase modulates cell growth and associates with poor outcome in human neuroblastoma
Nunes Xavier, Caroline E.; Aurtenetxe, Olaia; Zaldumbide Dueñas, Laura; López Almaraz, Ricardo; Erramuzpe Aliaga, Asier; Cortés Díaz, Jesús María; López Fernández de Villaverde, José Ignacio; Pulido Murillo, Rafael (BMC, 2019-12-14)
Background Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the ... -
Reactive Disruption of the Hippocampal Neurogenic Niche After Induction of Seizures by Injection of Kainic Acid in the Amygdala
Muro García, Teresa; Martín Suárez, Soraya; Espinosa, Nelson; Valcárcel Martín, Roberto; Marinas, Ainhoa; Zaldumbide Dueñas, Laura; Galbarriatu, Lara; Sierra Saavedra, Amanda; Fuentealba, Pablo; Encinas Pérez, Juan Manuel (Frontiers Media, 2019-08-20)
Adult neurogenesis persists in the adult hippocampus due to the presence of multipotent neural stem cells (NSCs). Hippocampal neurogenesis is involved in a range of cognitive functions and is tightly regulated by neuronal ... -
Snail heterogeneity in clear cell renal cell carcinoma
(Biomed Central, 2016-03-08)Background: Intratumor heterogeneity may be responsible of the unpredictable aggressive clinical behavior that some clear cell renal cell carcinomas display. This clinical uncertainty may be caused by insufficient sampling, ...