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Analysis of Protein Oxidative Modifications in Follicular Fluid from Fertile Women: Natural Versus Stimulated Cycles
(MDPI, 2018-11-27)
Oxidative stress is associated with obstetric complications during ovarian hyperstimulation in women undergoing in vitro fertilization. The follicular fluid contains high levels of proteins, which are the main targets of ...
Bone Health and Its Relationship with Impact Loading and the Continuity of Physical Activity throughout School Periods
(MDPI, 2019-08-14)
Bone is influenced by physical activity (PA) throughout life, but childhood and adolescence provide a key opportunity to maximize peak bone mass. Thus, it is important to identify the relationship between PA practiced in ...
A Randomized Controlled Trial Protocol to Test The Efficacy of a Dual-TaskMulticomponent Exercise Program in the Attenuation of Frailty in Long-Term Nursing Home Residents: Aging-ONDUAL-TASK Study
(Springer Nature, 2019-01-08)
BACKGROUND: The purpose of the Aging-ONDUAL-TASK study is to determine if a supervised dual-task program carried out in long-term nursing homes is able to attenuate frailty in a greater extent than the same multicomponent ...
Regulation of boar sperm functionality by the nitric oxidesynthase/nitric oxide system
(Springer, 2019-08)
Purpose Nitric oxide (NO) is a free radical synthesized mainly by nitric oxide synthases (NOSs). NO regulates many aspects in sperm physiology in different species. However, in vitro studies investigating NOS distribution, ...
Manipulation of bicarbonate concentration in sperm capacitation media improves in vitro fertilisation output in porcine species
(Biomed Central, 2019-03-11)
BackgroundThe in vivo concentration of bicarbonate (HCO3-), one of the essential sperm capacitating effectors, varies greatly in the different environments sperm go through from cauda epididymis to the fertilisation site. ...
Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential
(Elsevier, 2020-01)
PGC-1 alpha controls, to a large extent, the capacity of cells to respond to changing nutritional requirements and energetic demands. The key role of metabolic reprogramming in tumor development has highlighted the potential ...
Screening of Natural Stilbene Oligomers from Vitis vinifera for Anticancer Activity on Human Hepatocellular Carcinoma Cells
(MDPI, 2020-06-01)
The characterization of bioactive resveratrol oligomers extracted from Vitis vinifera canes has been recently reported. Here, we screened six of these compounds (ampelopsin A, trans-ε-viniferin, hopeaphenol, isohopeaphenol, ...
Influence of nutrient intake on antioxidant capacity, muscle damage and white blood cell count in female soccer players
(BioMed Central, 2012-07-19)
Background: Soccer is a form of exercise that induces inflammatory response, as well as an increase in free radicals potentially leading to muscle injury. Balanced nutritional intake provides important antioxidant vitamins, ...
miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression
(MDPI, 2020-11-17)
Insulin resistance (IR) is one of the key contributing factors in the development of type 2 diabetes mellitus (T2DM). However, the molecular mechanisms leading to IR are still unclear. The implication of microRNAs (miRNAs) ...
Mechanisms Responsible for the Trophic Effect of Beta-Adrenoceptors on the I-to Current Density in Type 1 Diabetic Rat Cardiomyocytes
(Karger, 2013)
Background/Aims: In diabetic ventricular myocytes, transient outward potassium current (I-to) amplitude is severely reduced because of the impaired catecholamine release that characterizes diabetic autonomic neuropathy. ...