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Localization and Function of the Cannabinoid CB1 Receptor in the Anterolateral Bed Nucleus of the Stria Terminalis

Puente Bustinza, Nagore; Elezgarai Gabantxo, Izaskun; Lafourcade, Mathieu; Reguero Acebal, Leire; Marsicano, Giovanni; Georges, François; Manzoni, Olivier J.; Grandes Moreno, Pedro Rolando (Public Library of Science, 2010-01-25)

Background: The bed nucleus of the stria terminalis (BNST) is involved in behaviors related to natural reward, drug addiction and stress. In spite of the emerging role of the endogenous cannabinoid (eCB) system in these ...

Visualization by High Resolution Immunoelectron Microscopy of the Transient Receptor Potential Vanilloid-1 at Inhibitory Synapses of the Mouse Dentate Gyrus

Canduela Pérez, Miren Josune; Mendizabal Zubiaga, Juan Luis; Puente Bustinza, Nagore; Reguero Acebal, Leire; Elezgarai Gabantxo, Izaskun; Ramos Uriarte, Almudena; Gerrikagoitia Marina, Inmaculada; Grandes Moreno, Pedro Rolando (Public Library Science, 2015-03-16)

We have recently shown that the transient receptor potential vanilloid type 1 (TRPV1), a non-selective cation channel in the peripheral and central nervous system, is localized at postsynaptic sites of the excitatory ...

GABAergic and Cortical and Subcortical Glutamatergic Axon Terminals Contain CB1 Cannabinoid Receptors in the Ventromedial Nucleus of the Hypothalamus

Reguero Acebal, Leire; Puente Bustinza, Nagore; Elezgarai Gabantxo, Izaskun; Mendizabal Zubiaga, Juan Luis; Canduela Pérez, Miren Josune; Buceta Salazar, Ianire; Ramos Uriarte, Almudena; Suárez, Juan; Rodríguez de Fonseca, Fernando; Marsicano, Giovanni; Grandes Moreno, Pedro Rolando (Public Library of Science, 2011-10)

Background: Type-1 cannabinoid receptors (CB1R) are enriched in the hypothalamus, particularly in the ventromedial hypothalamic nucleus (VMH) that participates in homeostatic and behavioral functions including food intake. ...

Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle

Arrabal, Sergio; Lucena, Miguel Angel; Canduela Pérez, Miren Josune; Ramos Uriarte, Almudena; Rivera, Patricia; Serrano, Antonia; Pavón, Francisco Javier; Decara, Juan; Vargas, Antonio; Baixeras, Elena; Martín-Rufián, Mercedes; Márquez, Javier; Fernández-Llébrez, Pedro; De Roos, Baukje; Grandes Moreno, Pedro Rolando; Rodríguez de Fonseca, Fernando; Suárez, Juan (Public Library Science, 2015-12-15)

Cannabinoid CB1 receptors peripherally modulate energy metabolism. Here, we investigated the role of CB1 receptors in the expression of glucose/pyruvate/tricarboxylic acid (TCA) metabolism in rat abdominal muscle. ...