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Genetic Variants Associated with Colorectal Adenoma Susceptibility
(PUBLIC LIBRARY SCIENCE, 2016-04-14)
Background
Common low-penetrance genetic variants have been consistently associated with colorectal cancer risk.
Aim
To determine if these genetic variants are associated also with adenoma susceptibility and may ...
Development and external validation of a faecal immunochemical test-based prediction model for colorectal cancer detection in symptomatic patients
(Biomed Central, 2016-08-31)
Background: Risk prediction models for colorectal cancer (CRC) detection in symptomatic patients based on available biomarkers may improve CRC diagnosis. Our aim was to develop, compare with the NICE referral criteria and ...
Risk of Advanced Neoplasia in First-Degree Relatives with Colorectal Cancer: A Large Multicenter Cross-Sectional Study
(Public Library Science, 2016-05)
Background. First-degree relatives (FDR) of patients with colorectal cancer have a higher risk of developing colorectal cancer than the general population. For this reason, screening guidelines recommend colonoscopy every ...