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Mechanisms of action of Methylthioadenosine: pathways implicated in neuroprotection in models of Multiple Sclerosis and other neurological diseases

Moreno, B.; Di Penta, Alessandra; Kerschensteiner, M.; Matute Almau, Carlos José; Ceña, V.; López, I.; Alberch, Jordi; Parent, J.; Serra, J.; Errea, O.; Villoslada, Pablo (BioMed Central, 2010-11-25)

Background Methylthioadenosine (MTA) has anti-oxidant and anti-proliferative properties and was shown to induce cell protection in hepatic cells. We previously demonstrated that exert immunomodulatory and neuroprotective ...