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Utilidad del test de sangre oculta en heces para el diagnóstico del cancer colorrectal en la practica clínica en atención primaria

Gutiérrez Stampa, María Angeles; Aguilar Gama, Vanessa; Bujanda Fernández de Pierola, Luis (Elsevier, 2020-05)

Risk of gastrointestinal cancer in a symptomatic cohort after a complete colonoscopy: role of faecal immunochemical test

Pin Vieito, Noel; Iglesias, María J; Remedios, David; Rodríguez Alonso, Lorena; Rodriguez Moranta, Francisco; Álvarez Sánchez, Victoria; Fernández Bañares, Fernando; Boadas, Jaume; Martínez Bauer, Eva; Campo, Rafael; Bujanda Fernández de Pierola, Luis; Ferrández, Ángel; Piñol, Virginia; Rodríguez Alcalde, Daniel; Guardiola, Jordi; Cubiella, Joaquín; COLONPREDICT study investigators (Baishideng Publishing, 2020-01-07)

BACKGROUND Faecal immunochemical test (FIT) has been recommended to assess symptomatic patients for colorectal cancer (CRC) detection. Nevertheless, some conditions could theoretically favour blood originating in proximal ...

Increased Th17-Related Cytokine Serum Levels in Patients With Multiple Polyps of Unexplained Origin

Alustiza, Miren; Hernández Illán, Eva; Juárez, Miriam; Giner Calabuig, Mar; Mira, Cristina; Martínez Roca, Alejandro; Bujanda Fernández de Pierola, Luis; Rodríguez Moranta, Francisco; Cubiella, Joaquín; De Castro, Luisa; Marín Gabriel, José Carlos; Herreros de Tejada, Alberto; Fernández Bañares, Fernando; Nicolás Pérez, David; Giménez, Paula; Martínez Cardona, Claudia; Francés, Rubén; Murcia, Oscar; Jover, Rodrigo (Wolters Kluwer, 2020-03)

OBJECTIVES: Most patients with multiple colonic polyps do not have a known genetic or hereditary origin. Our aim was to analyze the presence of inflammatory cytokines and levels of glucose, insulin, and C-reactive protein ...

Gene–Diet Interactions in Colorectal Cancer: Survey Design, Instruments, Participants and Descriptive Data of a Case–Control Study in the Basque Country

Alegría Lertxundi, Iker; Aguirre Gómez, Carmelo; Bujanda Fernández de Pierola, Luis; Fernández Fernández, Francisco Javier; Polo, Francisco; Ordovás, José María; Etxezarraga Zuluaga, María Carmen; Zabalza Estévez, Ignacio; Larzabal, Mikel; Portillo Villares, María Isabel; Martínez de Pancorbo Gómez, María de los Angeles; Palencia Madrid, Leire; García Etxebarria, Koldo; Rocandio Pablo, Ana María; Arroyo Izaga, Marta (MDPI, 2020-08-07)

Epidemiologic studies have revealed inconsistent evidence of gene-diet interaction in relation to colorectal cancer (CRC). The aim of this study was to analyze them in a sample of cases and controls from the population-based ...

Modeling Personalized Adjuvant TreaTment in EaRly stage coloN cancer (PATTERN)

Jongeneel, Gabrielle; Greuter, Marjolein J. E.; Van Erning, Felice N.; Koopman, Miriam; Medema, Jan P.; Kandimalla, Raju; Goel, Ajay; Bujanda Fernández de Pierola, Luis; Meijer, Gerrit A.; Fijneman, Remond J. A.; Van Oijen, Martijn G. H.; Ijzermans, Jan; Punt, Cornelis J. A.; Vink, Geraldine R.; Coupé, Veerle M. H. (Springer, 2020-09)

Aim To develop a decision model for the population-level evaluation of strategies to improve the selection of stage II colon cancer (CC) patients who benefit from adjuvant chemotherapy. Methods A Markov cohort model with ...

Colorectal Cancer Survival in 50- to 69-Year-Olds after Introducing the Faecal Immunochemical Test

Gutierrez Stampa, María Angeles; Aguilar Gama, Vanessa; Sarasqueta Eizaguirre, Cristina; Cubiella, Joaquín; Portillo Villares, María Isabel; Bujanda Fernández de Pierola, Luis (MDPI, 2020-08-25)

Population screening has improved early diagnosis of colorectal cancer (CRC). Nonetheless, most cases are diagnosed in symptomatic patients. Faecal immunochemical testing has been recommended for assessing patients with ...

A Novel Serum Metabolomic Profile for the Differential Diagnosis of Distal Cholangiocarcinoma and Pancreatic Ductal Adenocarcinoma

Macias, Rocio I. R.; Muñoz Bellvís, Luis; Sánchez Martín, Anabel; Arretxe Oliden Enara; Martínez Arranz, Ibon; Lapitz Damborenea, Ainhoa; Gutiérrez, M. Laura; La Casta, Adelaida; Alonso, Cristina; González, Luis M.; Avila, Matias A.; Martinez-Chantar, Maria L.; Castro, Rui E.; Bujanda Fernández de Pierola, Luis; Bañales Asurmendi, Jesús María; Marin, José J. G. (MDPI, 2020-05-31)

The diagnosis of adenocarcinomas located in the pancreas head, i.e., distal cholangiocarcinoma (dCCA) and pancreatic ductal adenocarcinoma (PDAC), constitutes a clinical challenge because they share many symptoms, are not ...

Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis

Lapitz Dambolenea, Ainhoa; Arbelaiz Cossio, Ander; O’Rourke, Colm J.; Lavín, José L.; Casta, Adelaida La; Ibarra, Cesar; Jimeno, Juan P.; Santos Laso, Alvaro; Izquierdo-Sanchez, Laura; Krawczyk, Marcin; Perugorria Montiel, María Jesús; Jiménez Agüero, Raúl; Sanchez-Campos, Alberto; Riaño Fernández, Ioana; Gónzalez, Esperanza; Lammert, Frank; Marzioni, Marco; Rodríguez Macías, Rocío Isabel; García Marín, Jose Juan; Karlsen, Tom H.; Bujanda Fernández de Pierola, Luis; Falcón Pérez, Juan Manuel; Andersen, Jesper B.; Aransay Bañares, Ana María; Rodrigues, Pedro M.; Bañales Asurmendi, Jesús María (MDPI, 2020-03-14)

Cholangiocarcinoma (CCA) comprises a group of heterogeneous biliary cancers with dismal prognosis. The etiologies of most CCAs are unknown, but primary sclerosing cholangitis (PSC) is a risk factor. Non-invasive diagnosis ...

Predictive Value of Carcinoembryonic Antigen in Symptomatic Patients without Colorectal Cancer: A Post-Hoc Analysis within the COLONPREDICT Cohort

Pin Vieito, Noel; Iglesias, María José; Remedios, David; Álvarez Sánchez, Victoria; Fernández Bañares, Fernando; Boadas, Jaume; Martínez Bauer, Eva; Campo, Rafael; Bujanda Fernández de Pierola, Luis; Ferrández, Ángel; Piñol, Virginia; Rodríguez Alcalde, Daniel; Menéndez Rodríguez, Martín; García Morales, Natalia; Pérez Mosquera, Cristina; Cubiella, Joaquín (MDPI, 2020-12-02)

We aimed to assess the risk of cancer in patients with abdominal symptoms after a complete colonoscopy without colorectal cancer (CRC), according to the carcinoembryonic antigen (CEA) concentration, as well as its diagnostic ...