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A beta oligomers promote oligodendrocyte differentiation and maturation via integrin beta 1 and Fyn kinase signaling
(Nature Publishing Group, 2019-06-06)
Alzheimer's disease (AD) is characterized by a progressive cognitive decline that correlates with the levels of amyloid beta-peptide (A beta) oligomers. Strong evidences connect changes of oligodendrocyte function with the ...
On-Line Monitoring of Blind Fastener Installation Process
(MDPI, 2019-04-01)
Blind fasteners are of special interest for aircraft construction since they allow working on joints where only one side is accessible, as is the case in many common aerospace box-type structures, such as stabilizers and ...
A Customized Pigmentation SNP Array Identifies a Novel SNP Associated with Melanoma Predisposition in the SLC45A2 Gene
(Public Library of Science, 2011-04-29)
As the incidence of Malignant Melanoma (MM) reflects an interaction between skin colour and UV exposure, variations in genes implicated in pigmentation and tanning response to UV may be associated with susceptibility to ...
Los requisitos para acceder a las magistraturas locales con base en los escritos de los juristas clásicos
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitateko Argitalpen Zerbitzua, 2011)
[ES] El artículo analiza los requisitos requeridos, avanzado el Principado, para
ser magistrado local, con base en la información proporcionada por los escritos de los juristas, en particular de los conocidos como clásicos ...
Liver sinusoidal endothelial cell ICAM-1 mediated tumor/endothelial crosstalk drives the development of liver metastasis by initiating inflammatory and angiogenic responses
(Nature Publishing, 2019-09-11)
The prometastatic stroma generated through tumor cells/host cells interaction is critical for metastatic growth. To elucidate the role of ICAM-1 on the crosstalk between tumor and primary liver sinusoidal endothelial cells ...
Implementing User Behaviour on Dynamic Building Simulations for Energy Consumption
(Sciendo-De Gruyter, 2019-12)
User behaviour influences the energy consumption of domestic properties with different range of variations and this has an effect on the results of building simulations based on default or general values, as opposed to ...
Broad Phenotypes of Disorders/Differences of Sex Development in MAMLD1 Patients Through Oligogenic Disease
(Frontiers Media, 2019-08-29)
Disorders/differences of sex development (DSD) are the result of a discordance between chromosomal, gonadal, and genital sex. DSD may be due to mutations in any of the genes involved in sex determination and development ...
Negative autoimmunity in a Spanish pediatric cohort suspected of type 1 diabetes, could it be monogenic diabetes?
(Public Library Science, 2019-07-31)
Objective
Monogenic diabetes can be misdiagnosed as type 1 or type 2 diabetes in children. The right diagnosis is crucial for both therapeutic choice and prognosis and influences genetic counseling. The main objective of ...
Social cognition in myotonic dystrophy type 1: Specific or secondary impairment?
(Public Library Science, 2018-09-24)
Aims
The cognitive profile of Myotonic Dystrophy type 1 (DM1) has been described in recent decades. Moreover, DM1 patients show lowered social engagement and difficulties in social-cognitive functions. The aim of the ...
Synthesis of mechanically strong waterborne poly(urethane-urea)s capable of self-healing at elevated temperatures
(Elsevier, 2019)
Although various chemistries have been introduced into polyurethanes in order to obtain self-healing abilities, implementing these materials in applications requiring high strength is challenging as strong materials imply ...