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Serological and Genetic Evidence for Altered Complement System Functionality in Systemic Lupus Erythematosus: Findings of the GAPAID Consortium
(Public Library Science, 2016-03-07)
Systemic lupus erythematosus is a chronic autoimmune disease with multifactorial ethiopathogenesis. The complement system is involved in both the early and late stages of disease development and organ damage. To better ...
LDLR and PCSK9 Are Associated with the Presence of Antiphospholipid Antibodies and the Development of Thrombosis in aPLA Carriers
(Public Library Science, 2016-01-28)
Introduction
The identification of the genetic risk factors that could discriminate non-thrombotic from thrombotic antiphospholipid antibodies (aPLA) carriers will improve prognosis of these patients. Several human ...
The impact of the Great Recession on mental health and its inequalities: the case of a Southern European region, 1997-2013
(Biomed Central, 2016-01-26)
Background: Numerous studies have shown that macroeconomic changes have a great influence on health, prompting different concerns in recent literature about the effects of the current recession. The objetive of the study ...
Sensing parasites: proteomic and advanced bio-detection alternatives
(Elsevier, 2016-03-16)
[EN] Parasitic diseases have a great impact in human and animal health. The gold standard for the diagnosis of the majority of parasitic infections is still conventional microscopy, which presents important limitations in ...
Adaptive coatings based on polyaniline for direct 2D observation of diffusion processes in microfluidic systems
(Elsevier, 2016-08)
[EN] Therefore the understanding and proper evaluation of the flow and mixing behaviour at microscale becomes a very important issue. In this study, the diffusion behaviour of two reacting solutions of HCI and NaOH were ...
Microcantilever arrays functionalised with spiropyran photoactive moieties as systems to measure photo-induced surface stress changes
(Elsevier, 2016-12)
[EN] Herein we investigate the feasibility of detecting photo-induced surface stress changes using the deflection response of cantilevers. For this purpose, silicon microcantilevers have been functionalised with spiropyran ...
Porous self-protonating spiropyran-based NIPAAm gels with improved reswelling kinetics
(Springer, 2016-02)
[EN] This study focuses on improving the speed ofactuation of poly(N-isopropylacrylamide)-based photoresponsive gels containing copolymerised spiropyran as the photoswitch and acrylic acid as the proton source. The improvement ...
Fluidic flow delay by ionogel passive pumps in microfluidic paper-based analytical devices
(Elsevier, 2016-10-05)
[EN] A new concept for fluid flow manipulation in microfluidic paper-based analytical devices (m-PADs) is presented by introducing ionogel materials as passive pumps. m-PADs were fabricated using a new doubleside contact ...
Multicenter prospective study on the burden of rotavirus gastroenteritis in children less than 3 years of age in Spain
(Biomed Central, 2016-10-10)
Background: Rotavirus is acknowledged as an important cause of paediatric gastroenteritis worldwide. In Spain, comprehensive data on the burden of rotavirus disease was lacking.
Methods: A prospective, multicenter, ...
Assessment of positive parenting programmes in the Autonomous Region of the Basque Country (Spain)
(Colegio Oficial de Psicólogos de Madrid, 2016-08)
This paper presents the results of a study aimed at identifying and assessing positive parenting programmes and activities carried out in the Autonomous Region of the Basque Country (ARBC), Spain. The study is a development ...