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dc.contributor.authorAmoruso, Lucia
dc.contributor.authorFinisguerra, A.
dc.contributor.authorUrgesi, C.
dc.date.accessioned2018-11-06T08:24:16Z
dc.date.available2018-11-06T08:24:16Z
dc.date.issued2018
dc.identifier.citationAmoruso, L., Finisguerra, A., & Urgesi, C. (2018). Autistic traits predict poor integration between top-down contextual expectations and movement kinematics during action observation. Scientific Reports, 8:16208. Doi: 10.1038/s41598-018-33827-8es_ES
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/10810/29563
dc.descriptionAvailable online 01 November 2018es_ES
dc.description.abstractAutism is associated with difficulties in predicting and understanding other people’s actions. There is evidence that autistic traits are distributed across a spectrum and that subclinical forms of autistic impairments can also be measured in the typical population. To investigate the association between autistic traits and motor responses to others’ actions, we quantified these traits and measured cortico-spinal excitability modulations in M1 during the observation of actions embedded in congruent, incongruent and ambiguous contexts. In keeping with previous studies, we found that actions observed in congruent contexts elicited an early facilitation of M1 responses, and actions observed in incongruent contexts, resulted in a later inhibition. Correlational analysis revealed no association between autistic traits and the facilitation for congruent contexts. However, we found a significant correlation between motor inhibition and autistic traits, specifically related to social skills and attention to details. Importantly, the influence of these factors was independent from each other, and from the observer’s gender. Thus, results suggest that individuals with higher social deficits and greater detail-processing style are more impaired in suppressing action simulation in M1 when a mismatch between kinematics and context occurs. This points to difficult integration between kinematics and contextual representations in the autistic-like brain.es_ES
dc.description.sponsorshipThis work was supported by grants from the European Commission (MCSA-H2020-NBUCA, grant N. 656881), the Ministero Istruzione Universita‘ e Ricerca (Futuro In Ricerca, FIR 2012, Prot. N. RBFR12F0BD; to C.U.), and from Istituto di Ricovero e Cura a Carattere Scientifico ‘E. Medea’ (Ricerca Corrente 2016, Ministero Italiano della Salute; to C.U.).es_ES
dc.language.isoenges_ES
dc.publisherScientific Reportses_ES
dc.relationinfo:eu-repo/grantAgreement/MC/H2020-NBUCA-656881es_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.titleAutistic traits predict poor integration between top-down contextual expectations and movement kinematics during action observationes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holderOpen Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. © The Author(s) 2018es_ES
dc.relation.publisherversionhttps://www.nature.com/srep/es_ES
dc.identifier.doi10.1038/s41598-018-33827-8


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