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Methylmercury Poisoning Induces Cardiac Electrical Remodeling and Increases Arrhythmia Susceptibility and Mortality
(MDPI, 2020-05-15)
This study aims to investigate the cardiac electrical remodeling associated with intoxication by methylmercury (MeHg). We evaluated the chronic effects of MeHg on in vivo electrocardiograms and on ex vivo action potentials ...
An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer
(MDPI, 2020-08-22)
(1) Background & Aims: The roles of different cells in the tumor microenvironment (TME) are critical to the metastatic process. The phenotypic transformation of the liver cells is one of the most important stages of the ...
Consideración integral del edadismo. Análisis de la relación entre estereotipos negativos del envejecimiento y las distintas dimensiones que conforman las personas mayores en dos contextos sociales distintos
(2020-12-17)
El edadismo o discriminación por edad, discriminación cada vez más prevalente en nuestra sociedad, influye negativamente en la salud y autonomía de las personas mayores. Aunque es un tema candente, destaca la ausencia de ...
Estudio de las cualidades psicométricas de un nuevo dispositivo para la valoración de la marcha en Esclerosis Múltiple: Fiabilidad, validez y sensibilidad del "Smart-tip".
(2022-11-10)
Antecedentes y objetivos: La Esclerosis Múltiple es una patología neurológica de origen inflamatorio que afecta fundamentalmente al sistema nervioso central, tratándose de la causa no traumática de discapacidad más frecuente ...
Videoconference-Based Physical Performance Tests: Reliability and Feasibility Study
(MDPI, 2022)
Validated tools to evaluate physical performance remotely with real-time supervision are lacking. We assessed test–retest and inter-rater reliability, as well as the feasibility of carrying out the five-repetition sit-to-stand ...
Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential
(Elsevier, 2020-01)
PGC-1 alpha controls, to a large extent, the capacity of cells to respond to changing nutritional requirements and energetic demands. The key role of metabolic reprogramming in tumor development has highlighted the potential ...
Effects of COVID-19 Lockdown on Physical Activity and Health-Related Quality of Life in Older Adults Who Regularly Exercise
(MDPI, 2021)
The aim of the study was to analyze the effect of social distancing on physical activity (PA) and Health-Related Quality of Life (HRQoL) in active Spanish older adults according to their physical functionality. The study ...
Ariketa fisikoko esku-hartze desberdinen eragina hirugarren adineko egoitzetan bizi diren adinekoen funtzio fisiko zein kognitiboan eta afektibitate egoeran
(2020-07-22)
[EU]Tesi honek ausazko entsegu kliniko bat barnehartzen du. Helburu nagusia ariketa fisikoan oinarritutako hiru esku-hartze desberdinen (osagai anitzeko ariketa fisikoko esku-hartzea, dual-task esku-hartzea, eta oinez ...
Serum Sestrin-1 Concentration Is Higher in Frail than Non-Frail Older People Living in Nursing Homes
(MDPI, 2022-01-19)
Given the increasing prevalence of frailty and its implications for public health, the identification of biomarkers to detect frailty is essential. Sestrin-1 is a protein with a protective role in muscle function. This ...
Impact of COVID-19 Confinement on Physical Activity and Sedentary Behaviour in Spanish University Students: Role of Gender
(MDPI, 2021-01-06)
During the COVID-19 pandemic, entire populations were instructed to live in home-confinement to prevent the expansion of the disease. Spain was one of the countries with the strictest conditions, as outdoor physical activity ...