Search
Now showing items 21-22 of 22
Design, synthesis and cytotoxic evaluation of diphenyl(quinolin-8-yl)phosphine oxides
(Elsevier, 2021-04)
A new strategy is reported for the synthesis of quinolinylphosphine oxides via the Povarov reaction between phosphorous aldimines and acetylenes. Moreover, these compounds were studied for in vitro cytotoxicity on a human ...
Synthesis, biological and computational evaluation of novel cyanomethyl vinyl ether derivatives
(Frontiers Media, 2024)
This work explores the biological evaluation of novel cyanomethyl vinyl ether derivatives as antiproliferative agents. Tubulin, crucial to microtubule structure and function, is a target for cancer therapies. In vitro ...