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Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response 

Gómez Fernández, Paloma; Urtasun Arricaberri, Andoni; Paton, Adrienne W.; Paton, James C.; Borrego, Francisco; Dersh, Devin; Argon, Yair; Alloza Moral, Iraide; Vandenbroeck, Koen (Frontiers Media, 2018-12-14)
The human IL22RA2 gene co-produces three protein isoforms in dendritic cells [IL-22 binding protein isoform-1 (IL-22BPi1), IL-22BPi2, and IL-22BPi3]. Two of these, IL-22BPi2 and IL-22BPi3, are capable of neutralizing the ...
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Chronic Migraine Is a Misnomer 

Álvaro González, Luis Carlos (Elsevier, 2017-05)
las lesiones son extensas o la sintomatología es muy intensase prefiere tratamiento quirúrgico8. En el caso de nuestrapaciente, el tratamiento con amitriptilina y diversos fárma-cos neuromoduladores solamente redujo de ...
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Expression Profiling Analysis Reveals Key MicroRNA– mRNA Interactions in Early Retinal Degeneration in Retinitis Pigmentosa 

Anasagasti, Ander; Ezquerra-Inchausti, Maitane; Barandika, Olatz; Muñoz-Culla, Maider ORCID; Caffarel, María M.; Otaegui Bichot, David; López de Munain Arregui, Adolfo José; Ruiz-Ederra, Javier (Association Research Vision Ophthalmology, 2018-05)
PURPOSE. The aim of this study was to identify differentially expressed microRNAs (miRNAs) that might play an important role in the etiology of retinal degeneration in a genetic mouse model of retinitis pigmentosa (rd10 ...
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Biomarcadores diagnósticos y de deterioro cognitivo en la enfermedad de Parkinson 

Delgado Alvarado, Manuel (2017-09-14)
La enfermedad de Parkinson es una enfermedad neurodegenerativa en la que, como en otras, el proceso fisiopatológico que conduce a la muerte de neuronas está presente desde tiempo antes del diagnóstico. Las manifestaciones ...
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Calpain 3 in skeletal muscle regeneration: Potential role in satellite cells and in the myogenic differentiation of iPSC-derived muscle progenitors 

Mateos Aierdi, Alba Judith (2017-12-18)
La distrofia de cinturas de tipo 2A (LGMD2A) es una enfermedad genética de herencia autosómicarecesiva, causada por mutaciones en el gen CAPN3, que codifica la proteasa muscular no lisosomalcalpaína 3. Los pacientes sufren ...
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Oxidative Stress and Proinflammatory Cytokines Contribute to Demyelination and Axonal Damage in a Cerebellar Culture Model of Neuroinflammation 

Di Penta, Alessandra; Moreno, Beatriz; Reix, Stephanie; Fernández Díez, Begoña; Villanueva, Maite; Errea, Oihana; Escala, Nagore; Vandenbroeck, Koen; Comella, Joan X.; Villoslada, Pablo (Public Library of Science, 2013-02-19)
Background: Demyelination and axonal damage are critical processes in the pathogenesis of multiple sclerosis (MS). Oxidative stress and pro-inflammatory cytokines elicited by inflammation mediates tissue damage. Metho ...
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Dbx1-Derived Pyramidal Neurons Are Generated Locally in the Developing Murine Neocortex 

Rueda-Alaña, Eneritz; Martínez-Garay, Isabel; Encinas Pérez, Juan Manuel; Molnár, Zoltán; García Moreno, Fernando (Frontiers Media, 2018-10-31)
The neocortex (NCx) generates at the dorsal region of the pallium in the forebrain. Several adjacent structures also contribute with neurons to NCx. Ventral pallium (VP) is considered to generate several populations of ...
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Purinergic P2X4 receptors modulate neuroinflammation and repair in experimental multiple sclerosis 

Zabala Olaizola, Alazne (2019-02-25)
La microglía examina el microambiente del sistema nervioso central para detectar señales de lesión o infección, y es esencial para el inicio y resolución de la inflamación inducida por patógenos o daño en los tejidos. ...
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APP depletion alters selective pre- and post-synaptic proteins 

Martinsson, lsak; Capetillo González de Zarate, Estibaliz; Faideau, Mathilde; Willén, Katarina; Esteras, Noemi; Frykman, Susanne; Tjernberg, Lars O.; Gouras, Gunnar K. (Elsevier, 2019-03)
The normal role of Alzheimer's disease (AD)-linked amyloid precursor protein (APP) in the brain remains incompletely understood. Previous studies have reported that lack of APP has detrimental effects on spines and ...
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Spinal cord injury induces astroglial conversion towards neuronal lineage 

Noristani, Harun Najib; Sabourin, Jean Charles; Boukhaddaoui, Hassan; Chan-Seng, Emilie; Gerber, Yannick Nicolas; Perrin, Florence Evelyne (Biomed Central, 2016-10-06)
Background: Neurons have intrinsic capability to regenerate after lesion, though not spontaneously. Spinal cord injury (SCI) causes permanent neurological impairments partly due to formation of a glial scar that is composed ...
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AuthorMatute, Carlos (50)González-Pinto, Ana María (42)López de Munain Arregui, Adolfo José (28)Vieta, Eduard (18)... View MoreTipo documentoinfo:eu-repo/semantics/article (298)info:eu-repo/semantics/doctoralThesis (124)info:eu-repo/semantics/other (1)Departamento (cas.)
Neurociencias (423)
Farmacología (17)Biología celular e histología (7)Fisiología (6)... View MoreDepartamento (eus.)Neurozientziak (422)Farmakologia (17)Fisiologia (6)Farmazia eta elikagaien zientziak (5)... View MoreSubjectMEDICINE (33)BIOCHEMISTRY AND MOLECULAR BIOLOGY (26)AGRICULTURAL AND BIOLOGICAL SCIENCES (25)CELLULAR AND MOLECULAR NEUROSCIENCE (20)... View MoreDate Issued2020 - 2023 (215)2010 - 2019 (202)2003 - 2009 (6)Language(ISO)eng (353)spa (67)eus (15)

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