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A Computational Analysis of Protein-Protein Interaction Networks in Neurodegenerative Diseases
(Biomed Central, 2008-06-20)
Background: Recent developments have meant that network theory is making an important contribution to the topological study of biological networks, such as protein-protein interaction (PPI) networks. The identification of ...
Skeleton based visual pattern recognition. Applications to tabletop interaction
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2009-12-10)
[EN]The practical context of this thesis work is natural interaction in Interactive
Multimedia Tabletops using visually recognized hand gestures. An
interaction language has been de ned for the speci c characteristics ...
Differential Micro RNA Expression in PBMC from Multiple Sclerosis Patients
(Public Library of Science, 2009-07-20)
Differences in gene expression patterns have been documented not only in Multiple Sclerosis patients versus healthy controls but also in the relapse of the disease. Recently a new gene expression modulator has been identified: ...
Prioritization of candidate cancer genes-an aid to oncogenomic studies
(Oxford University Press, 2008-10)
The development of techniques for oncogenomic analyses such as array comparative genomic hybridization, messenger RNA expression arrays and mutational screens have come to the fore in modern cancer research. Studies utilizing ...
A sensitivity study of bias and variance of k-fold cross-validation in prediction error estimation
(2009)
In the machine learning field the performance of a classifier is usually measured in terms of prediction error. In most real-world problems, the error cannot be exactly calculated and it must be estimated. Therefore, it’s ...
A Review of Estimation of Distribution Algorithms in Bioinformatics
(Biomed Central, 2008-09-11)
Evolutionary search algorithms have become an essential asset in the algorithmic toolbox for solving high-dimensional optimization problems in across a broad range of bioinformatics problems. Genetic algorithms, the most ...
MATEDA: A suite of EDA programs in Matlab
(2009)
This paper describes MATEDA-2.0, a suite of programs in Matlab for
estimation of distribution algorithms. The package allows the optimization of single and multi-objective problems with estimation of distribution
algorithms ...
A quantitative analysis of estimation of distribution algorithms based on Bayesian networks
(2009)
The successful application of estimation of distribution algorithms
(EDAs) to solve different kinds of problems has reinforced their candidature
as promising black-box optimization tools. However, their internal behavior
is ...
On the application of estimation of distribution algorithms to multi-marker tagging SNP selection
(2009)
This paper presents an algorithm for the automatic selection of a
minimal subset of tagging single nucleotide polymorphisms (SNPs) using an estimation of distribution algorithm (EDA). The EDA stochastically searches the ...
Gene Expression Profiling in Limb-Girdle Muscular Dystrophy 2A
(Public Library of Science, 2008-11-18)
Limb-girdle muscular dystrophy type 2A (LGMD2A) is a recessive genetic disorder caused by mutations in calpain 3 (CAPN3). Calpain 3 plays different roles in muscular cells, but little is known about its functions or in ...