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Disfunción de las células precursoras dérmicas asociada al envejecimiento cutáneo: SOX2 como regulador del destino del linaje celular
(2020-06-03)
Durante el envejecimiento se produce una disminución funcional progresiva de los tejidos, a la cual subyace la pérdida del potencial regenerativo por alteraciones en el funcionamiento de las células madre/precursoras ...
Identification of a biomarker panel for colorectal cancer diagnosis
(BioMed Central, 2012-01-26)
Background: Malignancies arising in the large bowel cause the second largest number of deaths from cancer in the Western World. Despite progresses made during the last decades, colorectal cancer remains one of the most ...
Cell Reprogramming, IPS Limitations, and Overcoming Strategies in Dental Bioengineering
(SAGE-Hindawi Access to Research, 2012-03-29)
The procurement of induced pluripotent stem cells, or IPS cells, from adult differentiated animal cells has the potential to revolutionize future medicine, where reprogrammed IPS cells may be used to repair disease-affected ...
Study of human dental pulp stem cells (hDPSCs) combined with titanium, decellularized adipose tissue and plasma derived products on osteoinduction for bone tissue engineering
(2021-07-01)
We studied the human Dental Pulp Stem Cells (hDPSCs) adherence, proliferation, viability and osteo-differentiation potential when cultured on widely used Ti6AL4V titanium surface and a new biomimetic porous surface (BASTM), ...
Role of notch and wnt signaling in metabolic and epigenetic reprogramming of human dental pulp stem cells (DPSCs)
(2019-03-01)
Las Células Stem de Pulpa Dental (DPSCs; en inglés) son células madre extraídas de la pulpa dental de terceros molares de pacientes. Presentan unas propiedades que las convierte en un recurso especialmente interesante para ...
Caracterización de las células de Schwann cutáneas: análisis de su origen embrionario e implicación en el desarrollo de neurofibromas dérmicos
(2018-07-18)
En la piel, y posiblemente en otros tejidos, la identificación de poblaciones celulares -stem- bajo un excesivo número de denominaciones ha generado confusión en el campo, debido a la reformulación constante de la nomenclatura ...
Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
(BioMed Central, 2011-08)
Background: Human melanoma frequently colonizes bone marrow (BM) since its earliest stage of systemic dissemination, prior to clinical metastasis occurrence. However, how melanoma cell adhesion and proliferation mechanisms ...
MMADHC Premature Termination Codons in the Pathogenesis of Cobalamin D Disorder: Potential of Translational Readthrough Reconstitution
(Elsevier, 2021-03)
Mutations in the MMADHC gene cause cobalamin D disorder (cblD), an autosomal recessive inborn disease with defects in intracellular cobalamin (cbl, vitamin B12) metabolism. CblD patients present methylmalonic aciduria ...
Effect of resveratrol on alcohol-induced mortality and liver lesions in mice
(BioMed Central, 2006-11-14)
Background
Resveratrol is a polyphenol with important antiinflammatory and antioxidant properties. We investigated the effect of resveratrol on alcohol-induced mortality and liver lesions in mice.
Methods
Mice were ...
Aplicación de tecnologías disruptivas en telemedicina para la cobertura universal de servicios de salud
(Instituto Nacional De Salud - MSP y BS, 2020-06)
[ES] La aplicación de tecnologías disruptivas en telemedicina facilita la accesibilidad a tecnologías diagnósticas de poblaciones remotas sin acceso a especialistas y mejora la cobertura universal de servicios de salud. ...