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Visual Outcomes and Management After Corneal Refractive Surgery: a Review
(Elsevier, 2018-06)
Corneal refractive surgery procedures are widely performed to permanently correct refractive errors. Overall, refractive surgeries are safe, predictable and present high rates of satisfaction. Nevertheless, the induced ...
The complex association between the antioxidant defense system and clinical status in early psychosis
(Public Library Science, 2018-04-26)
Oxidative stress is a pathophysiological mechanism potentially involved in psychiatric disorders. The objective of this study was to assess the relationship between total antioxidant status (TAS) and the functional status ...
Visual Outcomes And Management After Corneal Refractive Surgery: A Review
(Elsevier, 2018-04)
Corneal refractive surgery procedures are widely performed to permanently correct refractive errors. Overall, refractive surgeries are safe, predictable and present high rates of satisfaction. Nevertheless, the induced ...
Familial amyloidosis with polyneuropathy type 1 caused by transthyretin mutation Val50Met (Val30Met): 4 cases in a non-endemic area
(Elsevier, 2018-11)
Introduction: Transthyretin-related familial amyloid polyneuropathy (TTR-FAP) typically arises as an autonomic neuropathy primarily affecting small fibres and it occurs in adult patients in their second or third decades ...
Contribution of Neurons and Glial Cells to Complement-Mediated Synapse Removal during Development, Aging and in Alzheimer’s Disease
(Hindawi, 2018)
Synapse loss is an early manifestation of pathology in Alzheimer's disease (AD) and is currently the best correlate to cognitive decline. Microglial cells are involved in synapse pruning during development via the complement ...
Smooth muscle cell characterization and transcriptomic analysis in human carotid atherosclerotic plaques
(2018-10-19)
Las enfermedades cardiovasculares (CV) son una de las causas más importantes de discapacidad y muerte prematura en todo el mundo. Una de las causas subyacentes de las CV es la aterosclerosis. La aterosclerosis de carótida ...
Characterization of Carotid Smooth Muscle Cells during Phenotypic Transition
(MDPI, 2018-03)
Vascular smooth muscle cells (VSMCs) are central players in carotid atherosclerosis plaque development. Although the precise mechanisms involved in plaque destabilization are not completely understood, it is known that ...
Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response
(Frontiers Media, 2018-12-14)
The human IL22RA2 gene co-produces three protein isoforms in dendritic cells [IL-22 binding protein isoform-1 (IL-22BPi1), IL-22BPi2, and IL-22BPi3]. Two of these, IL-22BPi2 and IL-22BPi3, are capable of neutralizing the ...
Short-Term Exposure to Enriched Environment in Adult Rats Restores MK-801-Induced Cognitive Deficits and GABAergic Interneuron Immunoreactivity Loss
(Springer Science, 2018-01-01)
Perinatal injections of N-methyl-D-aspartate (NMDA) receptor antagonist in rodents emulate some cognitive impairments and neurochemical alterations, such as decreased GABAergic (gamma aminobutyric acid) interneuron ...
Myocardial MIBG scintigraphy in genetic Parkinson’s disease as a model for Lewy body disorders
(Springer-Verlag, 2018-10-15)
Purpose To identify myocardial sympathetic denervation patterns suggestive of Lewy body (LB) pathology in patients with genetic and idiopathic parkinsonisms by 123I-metaiodobenzylguanidine (MIBG) scintigraphy. Methods We ...