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Is There Such a Thing as a Genuine Cancer Stem Cell Marker? Perspectives from the Gut, the Brain and the Dental Pulp
(MDPI, 2020-11-27)
The conversion of healthy stem cells into cancer stem cells (CSCs) is believed to underlie tumor relapse after surgical removal and fuel tumor growth and invasiveness. CSCs often arise from the malignant transformation of ...
Soluble PD-L1 Is an Independent Prognostic Factor in Clear Cell Renal Cell Carcinoma
(MDPI, 2021-02-07)
(1). Background: Immunohistochemical (IHC) evaluation of programmed death-1 (PD-1) and its ligand (PD-L1) is being used to evaluate advanced malignancies with potential response to immune checkpoint inhibitors. We evaluated ...
Vasculogenesis from Human Dental Pulp Stem Cells Grown in Matrigel with Fully Defined Serum-Free Culture Media
(MDPI, 2020-11-09)
The generation of vasculature is one of the most important challenges in tissue engineering and regeneration. Human dental pulp stem cells (hDPSCs) are some of the most promising stem cell types to induce vasculogenesis ...
La heterogeneidad intratumoral en el carcinoma renal de células claras
(2016-10-21)
La heterogeneidad intratumoral (HI) es un evento inherente al desarrollo tumoral que podría ser responsable del comportamiento clínico agresivo imprevisto que muestran algunos carcinomas renales de células claras (CRCC). ...
Advances and Perspectives in Dental Pulp Stem Cell Based Neuroregeneration Therapies
(MDPI, 2021-03-29)
Human dental pulp stem cells (hDPSCs) are some of the most promising stem cell types for regenerative therapies given their ability to grow in the absence of serum and their realistic possibility to be used in autologous ...
Birsortze neuralean erabiltzeko hortz muineko ama zelulen gaitasun funtzionalaren azterketa
(2018-12-19)
Ezaguna da hortz muin helduak zelula ama populazio garrantzitsu bat duela barnean, hauei, hortz muineko zelula amak deritze (ingelesez, dental pulp stem cells, DPSCs). Oinarrizko egoeran aurkezten dituzten zelula neuralen ...
Neonatal multiple organ failure after perinatal asphyxia.
(Elsevier, 2022-10)
Perinatal asphyxia is an event with far-reaching consequences that can lead not only to the development of neonatal encephalopathy, but also to multiple organ failure (MOF). This ailment may result from the redistribution ...
Advances of high-order interactions in the human brain: Applications in aging and neurodegeneration.
(2022-10-05)
The human brain generates a large repertoire of spatio-temporal patterns, which supporta wide variety of motor, cognitive, and behavioral functions. The most acceptedhypothesis in modern neuroscience is that each of these ...
Wnt signaling reprograms metabolism in dental pulp stem cells
(Wiley, 2019-08)
Human dental pulp stem cells (DPSCs) can differentiate to a wide range of different cell lineages, and share some gene expression and functional similarities with pluripotent stem cells. The stemness of DPSCs can also be ...
Stem and Cancer Stem Cell Identities, Cellular Markers, Niche Environment and Response to Treatments to Unravel New Therapeutic Targets
(MDPI, 2021-01-02)
Adult stem cells are a partially quiescent cell population responsible for natural cell renewal and are found in many different regions of the body, including the brain, teeth, bones, muscles, skin, and diverse epithelia, ...