Browsing OpenAire by Author "Caillat, Christophe"
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Structure of HIV-1 gp41 with its Membrane Anchors Targeted by Neutralizing Antibodies
Caillat, Christophe; Guilligay, Delphine; Torralba Iturbe, Johana ; Friedrich, Nikolas; Nieva Escandón, José Luis; Trkola, Alexandra; Chipot, Christophe J.; Dehez, Francois L.; Weissenhorn, Winfried (eLife Sciences, 2021-04-19)The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate ...