Browsing OpenAire by Author "Valenti, Luca"

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      Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via DEPTOR-mTOR axis 

      Serrano Maciá, Marina; Simon, Jorge; González Rellán, María Jesús; Azkargorta, Mikel; Goikoetxea Usandizaga, Naroa; Lopitz Otsoa, Fernando; Saenz de Urturi Indart, Diego; Rodríguez Agudo, Rubén; Lachiondo Ortega, Sofía; Mercado Gómez, María; Gutiérrez de Juan, Virginia; Bizkarguenaga, Maider; Fernández Ramos, David; Buqué García, Xabier ORCID; Baselli, Guido A.; Valenti, Luca; Iruzubieta, Paula; Crespo, Javier; Villa, Erica; Bañales Asurmendi, Jesús María ORCID; Ávila, Matías A. ORCID; Marin, José J. G.; Aspichueta Celaá, Patricia; Sutherland, James D.; Barrio Olano, María Rosa; Mayor Martínez, Ugo ORCID; Elortza, Felix; Xirodimas, Dimitri; Nogueiras Pozo, Rubén; Delgado, Teresa C.; Martínez Chantar, María Luz ORCID (Elsevier, 2021-06-18)
      [EN] Objective: Neddylation is a druggable and reversible ubiquitin-like post-translational modification upregulated in many diseases, including liver fibrosis, hepatocellular carcinoma, and more recently, non-alcoholic ...
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      rs641738C>T nearMBOAT7is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis 

      Teo, Kevin; Abeysekera, Kushala W.M.; Adams, Leon; Aigner, Elmar; Anstee, Quentin M.; Bañales Asurmendi, Jesús María ORCID; Banerjee, Rajarshi; Basu, Priyadarshi; Berg, Thomas; Bhatnagar, Pallav; Buch, Stephan; Canbay, Ali; Caprio, Sonia; Chatterjee, Ankita; Chen, Yii-Der Ida; Chowdhury, Abhijit; Daly, Ann K.; Datz, Christian; De Gracia Hahn, Dana; DiStefano, Johanna K.; Dong, Jiawen; Duret, Amedine; EU-PNAFLD Investigators; Emdin, Connor; Fairey, Madison; Gerhard, Glenn S.; GOLD Consortium; Guo, Xiuqing; Hampe, Jochen; Hickman, Matthew; Heintz, Lena; Hudert, Christian; Hunter, Harriet; Kelly, Matt; Kozlitina, Julia; Krawczyk, Marcin; Lammert, Frank; Langenberg, Claudia; Lavine, Joel; Li, Lin; Lim, Hong Kai; Loomba, Rohit; Luukkonen, Panu K.; Melton, Phillip E.; Mori, Trevor A.; Palmer, Nicholette D.; Parisinos, Constantinos A.; Pillai, Sreekumar G.; Qayyum, Faiza; Reichert, Matthias C.; Romeo, Stefano; Rotter, Jerome I.; Im, Yu Ri; Santoro, Nicola; Schafmayer, Clemens; Speliotes, Elizabeth K.; Stender, Stefan; Stickel, Felix; Still, Christopher D.; Strnad, Pavel; Taylor, Kent D.; Tybjærg-Hansen, Anne; Umano, Giuseppina Rosaria; Utukuri, Mrudula; Valenti, Luca; Wagenknecht, Lynne E.; Wareham, Nicholas J.; Watanabe, Richard M.; Wattacheril, Julia; Yaghootkar, Hanieh; Yki-Järvinen, Hannele; Young, Kendra A.; Mann, Jake P. (Elsevier, 2021-01)
      Background & Aims: A common genetic variant near MBOAT7 (rs641738C>T) has been previously associated with hepatic fat and advanced histology in NAFLD; however, these findings have not been consistently replicated in the ...