BackExaminar OpenAire por departamento (eus.) "Fisiologia"
Now showing items 1-8 of 8
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Adiponectin, leptin, and IGF-1 are useful diagnostic and stratification biomarkers of NAFLD
Marques, Vanda; Afonso, Marta Bento; Bierig, Nina; Duarte-Ramos, Filipa; Santos Laso, Álvaro; Jiménez Agüero, Raúl; Eizaguirre Letamendia, Emma; Bujanda Fernández de Pierola, Luis
; Pareja Megía, María J.; Luís, Rita; Costa, Adília; Machado, Mariana Verdelho; Alonso, Cristina; Arretxe Oliden, Enara; Alustiza Echeberria, José María; Krawczyk, Marcin; Lammert, Frank; Tiniakos, Dina G.; Flehmig, Bertram; Cortez-Pinto, Helena; Bañales Asurmendi, Jesús María ; Castro, Rui E.; Normann, Andrea; Rodrigues, Cecilia M. P. (Frontiers Media, 2021-06-23)
[EN] Background: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease where liver biopsy remains the gold standard for diagnosis. Here we aimed to evaluate the role of circulating adiponectin, ... -
Liver metastases of intrahepatic Cholangiocarcinoma: implications for an updated staging system
Lamarca, Angela; Santos Laso, Álvaro; Utpatel, Kirsten; La Casta, Adelaida; Stock, Simone; Forner, Alejandro; Adeva, Jorge; Folseraas, Trine; ; Macias, Rocio I. R.; Krawczyk, Marcin; Krawczyk, Marek; Cardinale, Vincenzo; Braconi, Chiara; Alvaro, Domenico; ; Bañales Asurmendi, Jesús María; Valle, Juan W.; European Network for the Study of Cholangiocarcinoma (ENS-CCA) (Wiley, 2021-06-18)
[EN] BACKGROUND AND AIMS: Intrahepatic cholangiocarcinoma (iCCA) with liver metastases is perceived to have a poor prognosis, but the American Joint Committee on Cancer (AJCC) classifies them as early stage in the absence ... -
Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential
Prieto, Ignacio; Rubio Alarcón, Carmen; García Gómez, Raquel; Berdún, Rebeca; Urgel, Tamara; Portero, Manuel; Pamplona, Reinald; Martínez Ruiz, Antonio; Ruiz Sanz, José Ignacio; Ruiz Larrea, María Begoña; Jove, Mariona; Cerdán, Sebastián; Monsalve, María (Elsevier, 2020-01)
PGC-1 alpha controls, to a large extent, the capacity of cells to respond to changing nutritional requirements and energetic demands. The key role of metabolic reprogramming in tumor development has highlighted the potential ... -
Mineralocorticoid Receptor Modulation by Dietary Sodium Influences NAFLD Development in Mice
(Elsevier, 2021-04-30)Introduction and Objectives Nonalcoholic-fatty-liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome (MetS). Mineralocorticoid receptor (MR) activation is associated with increased risk of ... -
Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via DEPTOR-mTOR axis
; ; ; ; ; ; ; ; ; ; ; ; ; Buqué García, Xabier; ; ; ; ; ; Bañales Asurmendi, Jesús María ; Ávila, Matías A. ; ; ; ; ; Mayor Martínez, Ugo ; ; ; ; ; Martínez Chantar, María Luz (Elsevier, 2021-06-18)
[EN] Objective: Neddylation is a druggable and reversible ubiquitin-like post-translational modification upregulated in many diseases, including liver fibrosis, hepatocellular carcinoma, and more recently, non-alcoholic ... -
Physiological modules for generating discrete and rhythmic movements: Component analysis of EMG signals
(Frontiers Research Foundation, 2015-01-09)A central question in Neuroscience is that of how the nervous system generates the spatiotemporal commands needed to realize complex gestures, such as handwriting. A key postulate is that the central nervous system (CNS) ... -
Survival of Frail Elderly with Delirium
Cano Escalera, Guillermo; ; Irazusta Astiazaran, Jon; Labayen Goñi, Idoya ; Besga Basterra, Ariadna (MDPI, 2022-02-16)
This study aims to determine when frailty increases the risks of delirium mortality. Hospital patients falling into the elderly frail or pre-frail category were recruited, some without delirium, some with delirium at ... -
Systematic analysis of chemical-protein interactions from zebrafish embryo by proteome-wide thermal shift assay, bridging the gap between molecular interactions and toxicity pathways
(Elsevier, 2021-10-30)[EN]The molecular interaction between chemicals and proteins often promotes alteration of cellular function. One of the challenges of the toxicology is to predict the impact of exposure to chemicals. Assessing the impact ...