BackExaminar OpenAire por departamento (eus.) "Medikuntza"
Now showing items 1-19 of 19
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Adiponectin, leptin, and IGF-1 are useful diagnostic and stratification biomarkers of NAFLD
Marques, Vanda; Afonso, Marta Bento; Bierig, Nina; Duarte-Ramos, Filipa; Santos Laso, Álvaro; Jiménez Agüero, Raúl; Eizaguirre Letamendia, Emma; Bujanda Fernández de Pierola, Luis
; Pareja Megía, María J.; Luís, Rita; Costa, Adília; Machado, Mariana Verdelho; Alonso, Cristina; Arretxe Oliden, Enara; Alustiza Echeberria, José María; Krawczyk, Marcin; Lammert, Frank; Tiniakos, Dina G.; Flehmig, Bertram; Cortez-Pinto, Helena; Bañales Asurmendi, Jesús María ; Castro, Rui E.; Normann, Andrea; Rodrigues, Cecilia M. P. (Frontiers Media, 2021-06-23)
[EN] Background: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease where liver biopsy remains the gold standard for diagnosis. Here we aimed to evaluate the role of circulating adiponectin, ... -
Cholangiocarcinoma 2020: the next horizon in mechanisms and management
Bañales Asurmendi, Jesús María; ; ; ; ; ; ; ; Andersen, Jesper B.; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (Springer Nature, 2020-06-30)
[EN] Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant tumours that can arise at any point of the biliary tree. Their incidence is increasing globally, currently accounting for ~15% ... -
Cholangiocarcinoma landscape in Europe: Diagnostic, prognostic and therapeutic insights from the ENSCCA Registry
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Andersen, Jesper B.; ; ; Bujanda Fernández de Pierola, Luis; ; ; ; Bañales Asurmendi, Jesús María (Elsevier, 2022-05)
Background & Aims: Cholangiocarcinoma (CCA) is a rare and heterogeneous biliary cancer, whose incidence and related mortality is increasing. This study investigates the clinical course of CCA and subtypes (intrahepatic ... -
Colorectal Cancer Genetic Variants Are Also Associated with Serrated Polyposis Syndrome Susceptibility
Arnau Collell, Coral; Soares de Lima, Yasmin; Díaz Gay, Marcos; Muñoz, Jenifer; Carballal, Sabela; Bonjoch, Laia; Moreira, Leticia; Lozano, Juan José; Ocaña, Teresa; Cuatrecasas, Miriam; Díaz de Bustamante, Aranzazu; Castells, Antoni; Capella, Gabriel; Bujanda Fernández de Pierola, Luis; Cubiella, Joaquín; Rodríguez Alcalde, Daniel; Balaguer, Francesc; Ruiz Ponte, Clara; Valle, Laura; Moreno, Víctor; Castellví Bel, Sergi (BMJ Publishing Group, 2020-10)
Background Serrated polyposis syndrome (SPS) is a clinical entity characterised by large and/ormultiple serrated polyps throughout the colon and increased risk for colorectal cancer (CRC). The basis for SPS genetic ... -
Consumption of Caffeinated Beverages and Kidney Function Decline in an Elderly Mediterranean Population with Metabolic Syndrome
; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (Nature, 2021-03-31)
It remains unclear whether caffeinated beverages could have deleterious renal effects in elderly population with underlying comorbid conditions. We investigated the associations between coffee, tea, or caffeine intake and ... -
Contribution of cardio-vascular risk factors to depressive status in the PREDIMED-PLUS Trial. A cross-sectional and a 2-year longitudinal study
; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (Public Library Science, 2022-04-13)
BACKGROUND: Cardio-vascular disease and depression are thought to be closely related, due to shared risk factors. The aim of the study was to determine the association between cardio-vascular risk (CVR) factors and depressive ... -
Development and external validation of a faecal immunochemical test-based prediction model for colorectal cancer detection in symptomatic patients
Cubiella, Joaquín; Vega, Pablo; Salve, María; Díaz-Ondina, Marta; Alves, Maria Teresa; Quintero, Enrique; Álvarez-Sánchez, Victoria; Fernández-Bañares, Fernando; Boadas, Jaume; Campo, Rafel; Bujanda Fernández de Pierola, Luis; Clofent, Joan; Ferrandez, Ángel; Torrealba, Leyanira; Piñol, Virginia; Rodríguez-Alcalde, Daniel; Hernández, Vicent; Fernández-Seara, Javier; COLONPREDICT study investigators (Biomed Central, 2016-08-31)
Background: Risk prediction models for colorectal cancer (CRC) detection in symptomatic patients based on available biomarkers may improve CRC diagnosis. Our aim was to develop, compare with the NICE referral criteria and ... -
Factors associated with successful dietary changes in an energy-reduced Mediterranean diet intervention: a longitudinal analysis in the PREDIMED-Plus trial
; Alonso Gómez, Ángel María (Springer, 2022)
[EN] Purpose Long-term nutrition trials may fail to respond to their original hypotheses if participants do not comply with the intended dietary intervention. We aimed to identify baseline factors associated with successful ... -
Fruit and Vegetable Consumption is Inversely Associated with Plasma Saturated Fatty Acids at Baseline in Predimed Plus Trial
; ; ; ; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (Wiley, 2021-09)
Scope Plasma fatty acids (FAs) are associated with the development of cardiovascular diseases and metabolic syndrome. The aim of our study is to assess the relationship between fruit and vegetable (F&V) consumption and ... -
Impact of Positive Lymph Nodes and Resection Margin Status on the Overall Survival of Patients with Resected Perihilar Cholangiocarcinoma: The ENSCCA Registry
; Bañales Asurmendi, Jesús María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (MDPI, 2022-05-12)
Background: Lymph node metastasis and positive resection margins have been reported to be major determinants of overall survival (OS) and poor recurrence-free survival (RFS) for patients who underwent resection for perihilar ... -
Influence of MUC5B gene on antisynthetase syndrome
(Nature, 2020-01-29)MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ... -
Influence of MUC5B gene on antisynthetase syndrome
(Nature, 2020-01-29)MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ... -
Mediterranean diet and quality of life: Baseline cross-sectional analysis of the PREDIMED-PLUS trial
(Public Libray fo Science, 2018-06-18)We assessed if a 17-item score capturing adherence to a traditional Mediterranean diet (MedDiet) was associated with better health-related quality of life among older Spanish men and women with overweight or obesity harboring ... -
Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Bujanda Fernández de Pierola, Luis; ; Andersen, Jesper B.; ; ; Bañales Asurmendi, Jesús María (MDPI, 2020-03-14)
Cholangiocarcinoma (CCA) comprises a group of heterogeneous biliary cancers with dismal prognosis. The etiologies of most CCAs are unknown, but primary sclerosing cholangitis (PSC) is a risk factor. Non-invasive diagnosis ... -
rs641738C>T nearMBOAT7is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis
Teo, Kevin; Abeysekera, Kushala W.M.; Adams, Leon; Aigner, Elmar; Anstee, Quentin M.; Bañales Asurmendi, Jesús María; Banerjee, Rajarshi; Basu, Priyadarshi; Berg, Thomas; Bhatnagar, Pallav; Buch, Stephan; Canbay, Ali; Caprio, Sonia; Chatterjee, Ankita; Chen, Yii-Der Ida; Chowdhury, Abhijit; Daly, Ann K.; Datz, Christian; De Gracia Hahn, Dana; DiStefano, Johanna K.; Dong, Jiawen; Duret, Amedine; EU-PNAFLD Investigators; Emdin, Connor; Fairey, Madison; Gerhard, Glenn S.; GOLD Consortium; Guo, Xiuqing; Hampe, Jochen; Hickman, Matthew; Heintz, Lena; Hudert, Christian; Hunter, Harriet; Kelly, Matt; Kozlitina, Julia; Krawczyk, Marcin; Lammert, Frank; Langenberg, Claudia; Lavine, Joel; Li, Lin; Lim, Hong Kai; Loomba, Rohit; Luukkonen, Panu K.; Melton, Phillip E.; Mori, Trevor A.; Palmer, Nicholette D.; Parisinos, Constantinos A.; Pillai, Sreekumar G.; Qayyum, Faiza; Reichert, Matthias C.; Romeo, Stefano; Rotter, Jerome I.; Im, Yu Ri; Santoro, Nicola; Schafmayer, Clemens; Speliotes, Elizabeth K.; Stender, Stefan; Stickel, Felix; Still, Christopher D.; Strnad, Pavel; Taylor, Kent D.; Tybjærg-Hansen, Anne; Umano, Giuseppina Rosaria; Utukuri, Mrudula; Valenti, Luca; Wagenknecht, Lynne E.; Wareham, Nicholas J.; Watanabe, Richard M.; Wattacheril, Julia; Yaghootkar, Hanieh; Yki-Järvinen, Hannele; Young, Kendra A.; Mann, Jake P. (Elsevier, 2021-01)
Background & Aims: A common genetic variant near MBOAT7 (rs641738C>T) has been previously associated with hepatic fat and advanced histology in NAFLD; however, these findings have not been consistently replicated in the ... -
Serum Metabolites as Diagnostic Biomarkers for Cholangiocarcinoma, Hepatocellular Carcinoma, and Primary Sclerosing Cholangitis
Bañales Asurmendi, Jesús María; ; ; ; ; ; ; ; ; ; ; ; ; Ávila, Matías A. ; Martínez Chantar, María Luz ; Bujanda Fernández de Pierola, Luis ; ; ; (Wiley, 2019-08)
Early and differential diagnosis of intrahepatic cholangiocarcinoma (iCCA) and hepatocellular carcinoma (HCC) by noninvasive methods represents a current clinical challenge. The analysis of low-molecular-weight metabolites ... -
Symptom or faecal immunochemical test based referral criteria for colorectal cancer detection in symptomatic patients: a diagnostic tests study
Herrero, Jesús-Miguel; Vega, Pablo; Salve, María; Bujanda Fernández de Pierola, Luis; Cubiella, Joaquín (Biomed Central, 2018-10-25)
BackgroundSymptom based referral criteria for colorectal cancer (CRC) detection are the cornerstone of the strategy to improve prognosis in CRC. In 2017, the National Institute for Health and Care Excellence (NICE) updated ... -
The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome
; ; ; ; ; ; ; Alonso Gómez, Ángel María; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; (MDPI, 2020-05-25)
The main objective of this study was to examine the relationship between the level of physical activity (PA) and the degree of obesity with health-related quality of life (HRQoL) in individuals with metabolic syndrome ... -
The MLH1 c.1852_1853delinsGC (p.K618A) Variant in Colorectal Cancer: Genetic Association Study in 18,723 Individuals
Abulí, Anna; Bujanda Fernández de Pierola, Luis; Mun, Jenifer; Buch, Stephan; Schafmayer, Clemens; Maiorana, Maria Valeria; Veneroni, Silvia; Van Wezel, Tom; Liu, Tao; Westers, Helga; Esteban-Jurado, Clara; Ocan, Teresa; Pique, Josep M.; Andreu, Montserrat; Jover, Rodrigo; Carracedo, Angel; Xicola, Rosa M.; Llor, Xavier; Castells, Antoni; The EPICOLON Consortium; Dunlop15, Malcolm; Hofstra, Robert; Lindblom, Annika; Wijnen, Juul; Peterlongo, Paolo; Hampe, Jochen; Ruiz- Ponte, Clara; Castellví-Bel, Sergi (Public Library Science, 2014-04-17)
Colorectal cancer is one of the most frequent neoplasms and an important cause of mortality in the developed world. Mendelian syndromes account for about 5% of the total burden of CRC, being Lynch syndrome and familial ...