Study of the in vivo folding of the potassium channel Kv7.2

Abstract

[EN] Arrest peptides were employed as a technique to study the cotranslational folding of cytosolic A and B helices of the potassium channel Kv7.2. The results show the potential of arrest peptides to study cotranslational folding. In the tested conditions, the A and B helices mostly do not cotranslationally fold in the ribosome vestibule.