Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature
dc.contributor.author | Zou, Yupiao | |
dc.contributor.author | Han, Jianlin | |
dc.contributor.author | Saghyan, Ashot S. | |
dc.contributor.author | Mkrtchyan, Anna F. | |
dc.contributor.author | Konno, Hiroyuki | |
dc.contributor.author | Moriwaki, Hiroki | |
dc.contributor.author | Izawa, Kunisuke | |
dc.contributor.author | Soloshonok, Vadym Anatolievch | |
dc.date.accessioned | 2020-07-13T10:27:54Z | |
dc.date.available | 2020-07-13T10:27:54Z | |
dc.date.issued | 2020-06-12 | |
dc.identifier.citation | Molecules 25(12) : (2020) // Article ID 2739 | es_ES |
dc.identifier.issn | 1420-3049 | |
dc.identifier.uri | http://hdl.handle.net/10810/45443 | |
dc.description.abstract | Tailor-made amino acids are indispensable structural components of modern medicinal chemistry and drug design. Consequently, stereo-controlled preparation of amino acids is the area of high research activity. Over last decade, application of Ni(II) complexes of Schiff bases derived from glycine and chiral tridentate ligands has emerged as a leading methodology for the synthesis of various structural types of amino acids. This review article summarizes examples of asymmetric synthesis of tailor-made α-amino acids via the corresponding Ni(II) complexes, reported in the literature over the last four years. A general overview of this methodology is provided, with the emphasis given to practicality, scalability, cost-structure and recyclability of the chiral tridentate ligands. | es_ES |
dc.description.sponsorship | This research was funded by the National Natural Science Foundation of China (No. 21761132021), and IKERBASQUE, Basque Foundation for Science. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | |
dc.subject | tailor-made amino acids | es_ES |
dc.subject | Schiff bases | es_ES |
dc.subject | asymmetric synthesis | es_ES |
dc.subject | chiral tridentate ligands | es_ES |
dc.subject | square-planar Ni(II) complexes | es_ES |
dc.title | Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2020-06-30T16:29:20Z | |
dc.rights.holder | 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/1420-3049/25/12/2739/htm | es_ES |
dc.identifier.doi | 10.3390/molecules25122739 | |
dc.departamentoes | Química orgánica I | |
dc.departamentoeu | Kimika organikoa I |
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Except where otherwise noted, this item's license is described as 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).