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dc.contributor.authorCarranza Fernandino, Teresa
dc.contributor.authorZalba Balda, Martín
dc.contributor.authorBarriola Baraibar, Mari Jose
dc.contributor.authorGuerrero Manso, Pedro Manuel ORCID
dc.contributor.authorDe la Caba Ciriza, María Coro ORCID
dc.date.accessioned2023-03-16T17:54:43Z
dc.date.available2023-03-16T17:54:43Z
dc.date.issued2023
dc.identifier.citationInternational Journal of Bioprinting 9(1) : (2023) // Article ID 645es_ES
dc.identifier.issn2424-7723
dc.identifier.issn2424-8002
dc.identifier.urihttp://hdl.handle.net/10810/60377
dc.description.abstractSterilization is a crucial step in the process of developing bioinks for tissue engineering applications. In this work, alginate/gelatin inks were subjected to three sterilization methods: ultraviolet (UV) radiation, filtration (FILT), and autoclaving (AUTO). In addition, to simulate the sterilization effect in a real environment, inks were formulated in two different media, specifically, Dulbecco’s Modified Eagle’s Medium (DMEM) and phosphate-buffered saline (PBS). First, rheological tests were performed to evaluate the flow properties of the inks, and we observed that UV samples showed shear thinning behavior, which was favorable for three dimensional (3D) printing. Furthermore, the 3D-printed constructs developed with UV inks showed better shape and size fidelity than those obtained with FILT and AUTO. In order to relate this behavior to the material structure, Fourier transform infrared (FTIR) analysis was carried out and the predominant conformation in protein was determined by deconvolution of the amide I band, which confirmed that the prevalence of a-helix structure was greater for UV samples. This work highlights the relevance of sterilization processes, which are essential for biomedical applications, in the research field of bioinkses_ES
dc.description.sponsorshipAuthors thank Basque Government (IT1658-22 and KK2022-00019) for the funding. T.C. also thanks Basque Government for her fellowship (PRE_2021_1_0254).es_ES
dc.language.isoenges_ES
dc.publisherWHIOCEes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectinkses_ES
dc.subjectthree-dimensional printinges_ES
dc.subjectconstructses_ES
dc.subjectsterilizationes_ES
dc.titleEffect of sterilization processes on alginate/gelatin inks for three-dimensional printinges_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holder(c) 2022 Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License.es_ES
dc.rights.holderAtribución 3.0 España*
dc.relation.publisherversionhttps://ijb.sg/index.php/int-j-bioprinting/article/view/645es_ES
dc.identifier.doi10.18063/ijb.v9i1.645
dc.departamentoesIngeniería química y del medio ambientees_ES
dc.departamentoeuIngeniaritza kimikoa eta ingurumenaren ingeniaritzaes_ES


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(c) 2022 Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License.
Except where otherwise noted, this item's license is described as (c) 2022 Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License.