New Approved Drugs Appearing in the Pharmaceutical Market in 2022 Featuring Fragments of Tailor-Made Amino Acids and Fluorine

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Ikusi/Ireki
Data
2023-04-22
Egilea
Wang, Nana
Mei, Haibo
Dhawan, Gagan
Zhang, Wei
Han, Jianlin ORCID
Soloshonok, Vadym Anatolievch ORCID
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Molecules 28(9) : (2023) // Article ID 3651
URI
http://hdl.handle.net/10810/61161
Laburpena
The strategic fluorination of oxidatively vulnerable sites in bioactive compounds is a relatively recent, widely used approach allowing us to modulate the stability, bio-absorption, and overall efficiency of pharmaceutical drugs. On the other hand, natural and tailor-made amino acids are traditionally used as basic scaffolds for the development of bioactive molecules. The main goal of this review article is to emphasize these general trends featured in recently approved pharmaceutical drugs.
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© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).
Bestelakorik adierazi ezean, itemaren baimena horrela deskribatzen da:© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).