Evaluating Efficacy of Antimicrobial and Antifouling Materials for Urinary Tract Medical Devices: Challenges and Recommendations
dc.contributor.author | Ramstedt, Madeleine | |
dc.contributor.author | Ribeiro, Isabel A. | |
dc.contributor.author | Bujdakova, Helena | |
dc.contributor.author | Mergulhão, Filipe | |
dc.contributor.author | Jordao, Luisa | |
dc.contributor.author | Thomsen, Peter | |
dc.contributor.author | Alm, Martin | |
dc.contributor.author | Burmølle, Mette | |
dc.contributor.author | Vladkova, Todorka Gancheva | |
dc.contributor.author | Can, Fusun | |
dc.contributor.author | Reches, Meital | |
dc.contributor.author | Riool, Martijn | |
dc.contributor.author | Barros, Alexandre | |
dc.contributor.author | Reis, Rui L. | |
dc.contributor.author | Meaurio Arrate, Emiliano | |
dc.contributor.author | Kikhney, Judith | |
dc.contributor.author | Moter, Annette | |
dc.contributor.author | Zaat, Sebastian | |
dc.contributor.author | Sjollema, Jelmer | |
dc.date.accessioned | 2024-02-08T11:19:16Z | |
dc.date.available | 2024-02-08T11:19:16Z | |
dc.date.issued | 2019-05 | |
dc.identifier.citation | Macromolecular Bioscience 19(5) : (2019) // Article ID 1800384 | es_ES |
dc.identifier.issn | 1616-5195 | |
dc.identifier.issn | 1616-5187 | |
dc.identifier.uri | http://hdl.handle.net/10810/65531 | |
dc.description.abstract | In Europe, the mean incidence of urinary tract infections in intensive care units is 1.1 per 1000 patient-days. Of these cases, catheter-associated urinary tract infections (CAUTI) account for 98%. In total, CAUTI in hospitals is estimated to give additional health-care costs of £1–2.5 billion in the United Kingdom alone. This is in sharp contrast to the low cost of urinary catheters and emphasizes the need for innovative products that reduce the incidence rate of CAUTI. Ureteral stents and other urinary-tract devices suffer similar problems. Antimicrobial strategies are being developed, however, the evaluation of their efficacy is very challenging. This review aims to provide considerations and recommendations covering all relevant aspects of antimicrobial material testing, including surface characterization, biocompatibility, cytotoxicity, in vitro and in vivo tests, microbial strain selection, and hydrodynamic conditions, all in the perspective of complying to the complex pathology of device-associated urinary tract infection. The recommendations should be on the basis of standard assays to be developed which would enable comparisons of results obtained in different research labs both in industry and in academia, as well as provide industry and academia with tools to assess the antimicrobial properties for urinary tract devices in a reliable way. | es_ES |
dc.description.sponsorship | COST (European Cooperation in Science and Technology). Grant Number: PTDC/BTM-SAL/29335/2017 Portuguese Government, Fundação para a Ciência e Tecnologia (FCT) Fundação para a Ciência e a Tecnologia. Grant Number: ptdc/btm-sal/29335/2017 European Cooperation in Science and Technology. Grant Number: TD1305 | |
dc.language.iso | eng | es_ES |
dc.publisher | WILEY-VCH | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | antimicrobial | es_ES |
dc.subject | device-associated urinary tract infections | |
dc.subject | in vitro | |
dc.subject | in vivo | |
dc.subject | material testing | |
dc.title | Evaluating Efficacy of Antimicrobial and Antifouling Materials for Urinary Tract Medical Devices: Challenges and Recommendations | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made | * |
dc.relation.publisherversion | https://onlinelibrary.wiley.com/doi/full/10.1002/mabi.201800384 | es_ES |
dc.identifier.doi | 10.1002/mabi.201800384 | |
dc.departamentoes | Ingeniería Minera y Metalúrgica y Ciencia de los Materiales | es_ES |
dc.departamentoeu | Meatze eta metalurgia ingeniaritza materialen zientzia | es_ES |
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Except where otherwise noted, this item's license is described as © 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made